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American Physiological Society Journals Online
Articles in PresS

APS Articles in PresS are accepted, peer-reviewed papers published online in manuscript form before they are copyedited and published in a printed issue of the APS journal to which they were submitted. Articles in PresS are published online within a few days of being accepted, thus giving Authors and Readers immediate, subscription-based access to the newest research. Future print publication may differ slightly from the Articles in PresS version as a result of copyediting; the graphics quality may also be different. On each article's first page, the publication date appears above the title, followed by the article's unique Digital Object Identifier (DOI).
Learn more about Articles in PresS.

Articles in PresS will be available for the following journals:

Physiological Genomics
AJP-Cell Physiology
AJP-Endocrinology and Metabolism
AJP-Gastrointestinal and Liver Physiology
AJP-Heart and Circulatory Physiology

AJP-Lung, Cellular and Molecular Physiology
AJP-Regulatory, Integrative and Comparative Physiology
AJP-Renal Physiology
Journal of Applied Physiology
Journal of Neurophysiology

AJP - Heart and Circulatory Physiology Articles in PresS: Last updated May 9, 2008

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

9 May 2008

Yumei Ye, Juan D Martinez, J. Regino Perez-Polo, Yu Lin, Barry F Uretsky, and Yochai Birnbaum: The role of eNOS, iNOS and NF ${kappa}$ B in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.01350.2007 [Abstract] [PDF]

Daniel M Purdham, Venkatesh Rajapurohitam, Asad Zeidan, Cathy Huang, Garrett J. Gross, and Morris Karmazyn: A Neutralizing Leptin Receptor Antibody Mitigates Hypertrophy and Hemodynamic Dysfunction in the Postinfarcted Rat Heart
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.91537.2007 [Abstract] [PDF]

Hiromutsu Tominaga, Hideki Katoh, Keiichi Odagiri, Yasuyo Takeuchi, Hirotaka Kawashima, Masao Saotome, Tsuyoshi Urushida, Hiroshi Satoh, and Hideharu Hayashi: Different Effects of Palmitoyl-L-carnitine and Palmitoyl-CoA on Mitochondrial Function in Rat Ventricular Myocytes
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.01307.2007 [Abstract] [PDF]

Dongqi Xing, Wenguang Feng, Laszlo G Not, Andrew P Miller, Yun Zhang, Yiu-Fai Chen, Erum Majid-Hassan, John C. Chatham, and Suzanne Oparil: Increased Protein O-GlcNAc Modification Inhibits Inflammatory and Neointimal Responses to Acute Endoluminal Arterial Injury
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.01259.2007 [Abstract] [PDF]

Miriam Weber, Martin Wehling, and Ralf Losel: Proteins interact with the cytosolic mineralocorticoid receptor depending on the ligand
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.00825.2007 [Abstract] [PDF]

Katherine A Radek, Elizabeth J Kovacs, Richard L. Gallo, and Luisa A. DiPietro: Acute Ethanol Exposure Disrupts VEGF Receptor Cell Signaling in Endothelial Cells
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.00699.2007 [Abstract] [PDF]

Rosa Mazza, Alfonsina Gattuso, Cinzia Mannarino, Bhawanjit K Brar, Sandra Francesca Barbieri, Bruno Tota, and Sushil K Mahata PhD: Catestatin (chromogranin A_344-364) is a novel cardiosuppressive agent: Inhibition of isoproterenol and endothelin signaling in the frog heart
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.00172.2008 [Abstract] [PDF]

Julian M Stewart, Indu Taneja, Neeraj Raghunath, Debbie Clarke, and Marvin S. Medow: Intradermal Angiotensin-II Administration Attenuates the Local Cutaneous Vasodilator Heating Response
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.00126.2008 [Abstract] [PDF]

Dean L. Kellogg, Jr., Joan Liu Zhao, and Yubo Wu: Endothelial Nitric Oxide Synthase Control Mechanisms in the Cutaneous Vasculature of Humans In Vivo
Am J Physiol Heart Circ Physiol (May 9, 2008). doi:10.1152/ajpheart.00082.2008 [Abstract] [PDF]

2 May 2008

Nitin T Aggarwal, Kathryn M Gauthier PhD, and William B. Campbell: 15-Lipoxygenase Metabolites Contribute to Age-related Reduction in Acetylcholine-induced Hypotention in Rabbits
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00054.2008 [Abstract] [PDF]

Qianwen Wang, Rajakumar V Donthi, Jianxun Wang, Alex J. Lange, Lewis J. Watson, Steve P Jones, and Paul N Epstein: Cardiac Phosphatase Deficient 6-Phosphofructo-2-kinase/Fructose-2,6-Bisphosphatase Increases Glycolysis, Hypertrophy and Myocyte Resistance to Hypoxia
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.91501.2007 [Abstract] [PDF]

Marketa Bebarova, Tom O'Hara, Jan L. M. C. Geelen, Roselie J. Jongbloed, Carl Timmermans, Yvonne H. Arens, Luz-Maria Rodriguez, Yoram Rudy, and Paul G.A. Volders: Subepicardial phase-0 block and discontinuous transmural conduction underlie right-precordial ST-segment elevation by a SCN5A loss-of-function mutation
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.91495.2007 [Abstract] [PDF]

Victor Martin Blanco, Javier E Stern M.D. PhD, and Jessica Andrea Filosa: Tone-dependent vascular responses to astrocyte-derived signals
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.91451.2007 [Abstract] [PDF]

Erik R. Kline, Dean J. Kleinhenz, Bill Liang, Sergey Dikalov, David M Guidot, C. Michael Hart, Dean P. Jones, and Roy L. Sutliff: Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.91447.2007 [Abstract] [PDF]

Motoyuki Iemitsu, Nobutake Shimojo, Seiji Maeda, Yoko Irukayama-Tomobe, Satoshi Sakai, Takeshi Ohkubo, Yukihisa Tanaka, and Takashi Miyauchi: The benefit of medium-chain triglyceride (MCT) therapy on cardiac function of SHR is associated with reversal of metabolic and signaling alterations
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01417.2006 [Abstract] [PDF]

Marcus Henze, Davin Hart, Allen M. Samarel, John Barakat, Laurie Eckert, and Karie E. Scrogin: Persistent alterations in heart rate variability, baroreflex sensitivity and anxiety-like behaviors during development of heart failure in the rat
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01373.2007 [Abstract] [PDF]

Rukhsana Gul, Seon-Young Kim, Kwang-Hyun Park, Byung Ju Kim, Se-Jin Kim, Mie-Jae Im, and Uh-Hyun Kim: A Novel Signaling Pathway of ADP-ribosyl Cyclase Activation by Angiotensin II in Adult Rat Cardiomyocytes
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01355.2007 [Abstract] [PDF]

Jonathan M Cordeiro, Megan Mazza, Robert Goodrow, Netha Ulahannan, Charles Antzelevitch, and Jose M Di Diego: Functionally Distinct Sodium Channels in Ventricular Epicardial and Endocardial Cells Contribute to a Greater Sensitivity of Epicardium to Electrical Depression
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01327.2007 [Abstract] [PDF]

Karl D Pendergrass, Nancy T Pirro, Brian M Westwood, Carlos M Ferrario, K. Bridget Brosnihan, and Mark C. Chappell: Sex Differences in Circulating and Renal Angiotensins of Hypertensive mRen(2).Lewis but not Normotensive Lewis Rats
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01277.2007 [Abstract] [PDF]

Paul David Chantler, Vojtech Melenovsky, Steven P Schulman, Gary Gerstenblith, Lewis C. Becker, Luigi Ferrucci, Jerome L. Fleg, Edward G Lakatta, and Samer S Najjar: The Sex-Specific Impact of Systolic Hypertension and Systolic Blood Pressure on Arterial-Ventricular Coupling at Rest and During Exercise
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01179.2007 [Abstract] [PDF]

Daming Zhuang, Qinghua Pu, Bogdan Ceacareanu, Yingzi Chang, Madhulika Dixit, and Aviv Hassid: Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.01105.2007 [Abstract] [PDF]

Mark A Christman II, Douglas J Goetz, Eric Dickerson, Kelly D McCall, Christopher J Lewis, Fabian Benencia, Mitchell J Silver, Leonard D Kohn, and Ramiro Malgor: Wnt5a is Expressed in Murine and Human Atherosclerotic Lesions
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00982.2007 [Abstract] [PDF]

Reuben Howden, Eric Liu, Laura Miller-DeGraff, Heather L Keener, Christopher Walker, James A Clark, Page H Myers, Douglas Clay Rouse, Tim Wiltshire, and Steven R. Kleeberger: THE GENETIC CONTRIBUTION TO HEART RATE AND HEART RATE VARIABILITY IN QUIESCENT MICE
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00941.2007 [Abstract] [PDF]

Souad Belmadani, Mouard Zerfaoui, Hamid A Boulares, Desiree I Palen, and Khalid Matrougui: Microvessels VSMC Contribute to Collagen Type-I deposition Through ERK1/2 MAP-kinase, ${alpha}$ v ${beta}$ 3-Integrin and TGF ${beta}$ 1 in Response to Angiotensin II and High Glucose
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00341.2008 [Abstract] [PDF]

Song-Jung Kim, Maha Abdellatif M.D., PhD, Sharat Koul, and George J. Crystal PhD: Chronic Treatment with Insulin-like Growth Factor-1 Enhances Myocyte Contraction by Upregulation of Akt-SERCA2a Signaling Pathway
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00298.2008 [Abstract] [PDF]

Dhananjay K Kaul, Xiaoqin Zhang, Trisha Dasgupta, and Mary E Fabry: Arginine Therapy of Transgenic-Knockout Sickle Mice Improves Microvascular Function by Reducing Non-Nitric Oxide Vasodilators, Hemolysis and Oxidative Stress
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00162.2008 [Abstract] [PDF]

Ryo Takeda, Etsu Suzuki, Masao Takahashi, Shigeyoshi Oba, Hiroaki Nishimatsu, Kenjiro Kimura, Tetsuo Nagano, Ryozo Nagai, and Yasunobu Hirata: Calcineurin Is Critical for Sodium-Induced Neointimal Formation in Normotensive And Hypertensive Rats
Am J Physiol Heart Circ Physiol (May 2, 2008). doi:10.1152/ajpheart.00031.2008 [Abstract] [PDF]

25 April 2008

Jian Cui, Raman Moradkhan, Vernon Mascarenhas, Afsana Momen, and Lawrence I. Sinoway: Cyclooxygenase inhibition attenuates sympathetic responses to muscle stretch in humans
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.91505.2007 [Abstract] [PDF]

Chiara Foglieni, Francesco Maisano, Lorella Dreas, Alessio Giazzon, Giacomo Ruotolo, Elisabetta Ferrero, Laura Li Volsi, Stefano Coli, Gianfranco Sinagra, Bartolo Zingone, Ottavio Alfieri, Anton E. Becker, and Attilio Maseri: Mild inflammatory activation of mammary arteries in patients with acute coronary syndromes
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.91428.2007 [Abstract] [PDF]

Yuan Li, Magda Descorbeth, and Madhu B Anand-Srivastava: Role of oxidative stress in high glucose-induced decreased expression of Gi ${alpha}$ proteins and adenylyl cyclase signaling in vascular smooth muscle cells
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.91422.2007 [Abstract] [PDF]

Masao Takahashi, Etsu Suzuki, Ryo Takeda, Shigeyoshi Oba, Hiroaki Nishimatsu, Kenjiro Kimura, Tetsuo Nagano, Ryozo Nagai, and Yasunobu Hirata: Angiotensin II and Tumor Necrosis Factor- ${alpha}$ Synergistically Promote Monocyte Chemoattractant Protein-1 Expression: Roles of NF ${kappa}$ B, p38 and Reactive Oxygen Species
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.91406.2007 [Abstract] [PDF]

Zhen Li, Changqing Yu, Yu Han, Hongmei Ren, Weibin Shi, Chunjiang Fu, Duofen He, Lan Huang, Chengming Yang, Xukai Wang, Lin Zhou, Laureano D Asico, Chunyu Zeng, and Pedro A. Jose: Inhibitory Effect of D₁-like and D₃ Dopamine Receptors on Norepinephrine-induced Proliferation in Vascular Smooth Muscle Cells
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.01344.2007 [Abstract] [PDF]

Nina D Ullrich, Andree Krust, Peter Collins, and Kenneth T MacLeod: Genomic deletion of estrogen receptors ER ${alpha}$ and ${beta}$ does not alter estrogen-mediated inhibition of Ca²⁺ influx and contraction in murine cardiomyocytes
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.01225.2007 [Abstract] [PDF]

Donglin Guo, Lindon H Young, Chinmay Patel, Zhen Jiao, Ying Wu, Tengxian Liu, Peter R Kowey, and Gan-xin Yan: Calcium-activated chloride current contributes to action potential alternations in left ventricular hypertrophy rabbit
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.01032.2007 [Abstract] [PDF]

Tammo Delhaas, Wilco Kroon, Wim Decaluwe, Mirjam Rubbens, Peter Bovendeerd, and Theo Arts: Structure and torsion of the normal and situs inversus totalis cardiac left ventricle; Part I: experimental data in human
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00876.2007 [Abstract] [PDF]

Ning Zou, Lihua Ao, Joseph C Cleveland, Jr., Xiaoping Yang, Xin Su, Guang-Yun Cai, Anirban Banerjee, David A Fullerton, and Xianzhong Meng: Critical role of extracellular heat shock cognate protein 70 in myocardial inflammatory response and cardiac dysfunction following global ischemia/reperfusion
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00299.2008 [Abstract] [PDF]

Peter J Leary, Surender Rajasekaran, R. Ray Morrison, Elaine I Tuomanen, Thomas K Chin, and Polly A. Hofmann: A Cardioprotective Role for Platelet Activating Factor Through NOS Dependent S-Nitrosylation
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00269.2008 [Abstract] [PDF]

Farisa Syeda, Elizabeth Tullis, Arthur S Slutsky, and Haibo Zhang: Human neutrophil peptides upregulate expression of COX-2 and endothelin-1 by inducing oxidative stress
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00211.2008 [Abstract] [PDF]

Garrett J. Gross, Kathryn M Gauthier PhD, Jeannine Moore, John R. Falck, Bruce D Hammock, William B. Campbell, and Kasem Nithipatikom: Effects of the Selective EET Antagonist, 14,15-EEZE, on Cardioprotection Produced by Exogenous or Endogenous EETs in the Canine Heart
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00186.2008 [Abstract] [PDF]

Takaaki Fujii, Mitsuho Onimaru, Yoshikazu Yonemitsu, Hiroyuki Kuwano, and Katsuo Sueishi: Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00149.2008 [Abstract] [PDF]

Cedric Filipe, Lætitia Lam Shang Leen, Laurent Brouchet, Audrey Billon, Vincent Benouaich, Vincent Fontaine, Pierre Gourdy, Françoise Lenfant, Jean-François Arnal, Alain-Pierre Gadeau, and Henrik Laurell: Estradiol accelerates endothelial healing through the retrograde commitment of uninjured endothelium
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00129.2008 [Abstract] [PDF]

Micheline Monteiro de Resende and Andrew S Greene PhD: Effect of Angiotensin II on Endothelial Cell Apoptosis and Survival and its Impact on Skeletal Muscle Angiogenesis after Electrical Stimulation
Am J Physiol Heart Circ Physiol (April 25, 2008). doi:10.1152/ajpheart.00095.2008 [Abstract] [PDF]

18 April 2008

Kamakshi Sachidanandam, Mostafa M Elgebaly, Alex K harris, Jim R Hutchinson, Erin M Mezzetti, Vera Portik-Dobos, and Adviye Ergul: Effect of Chronic and Selective Endothelin Receptor Antagonism on Microvascular Function in Type 2 Diabetes
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.91487.2007 [Abstract] [PDF]

Mohammad N Jameel, Xiaohong Wang, Marcel H.J. Eijgelshoven, Abdul Mansoor, and Jianyi Zhang: Transmural Distribution of Metabolic Abnormalities and Glycolytic Activity during Dobutamine Induced Demand Ischemia
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.01383.2007 [Abstract] [PDF]

Jeffrey G Williams, Caroline Ojaimi, Khaled Qanud, Suhua Zhang, Xiaobin Xu, Fabio A. Recchia, and Thomas H Hintze: Coronary Nitric Oxide production controls cardiac substrate metabolism during pregnancy in the dog
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.01196.2007 [Abstract] [PDF]

Steven M Kerfoot, Graciela Andonegui, Claudine S Bonder, and Lixin Liu: Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00984.2007 [Abstract] [PDF]

Vincent G DeMarco, Javad Habibi, Adam T Whaley-Connell, Rebecca Irene Schneider, Randall Lane Heller, James P Bosanquet, Melvin R Hayden, Kimberly Delcour, Shawna A Cooper, Bradley T Andresen, James R Sowers, and Kevin C Dellsperger: Oxidative Stress Contributes to Pulmonary Hypertension in the Transgenic (mRen2) 27 Ren2 Rat
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00953.2007 [Abstract] [PDF]

Wilco Kroon, Tammo Delhaas, Peter Bovendeerd, and Theo Arts: Structure and torsion in the normal and situs inversus totalis cardiac left ventricle; Part II: modeling cardiac adaptation to mechanical load
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00877.2007 [Abstract] [PDF]

Philippe Morimont, Bernard Lambermont, Alexandre Ghuysen, Paul Gerard, Philippe H Kolh, Patrizio Lancellotti, Vincent Tchana-Sato, Thomas Desaive, and Vincent D'Orio: Effective arterial elastance as an index of pulmonary vascular load
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00796.2007 [Abstract] [PDF]

Fanrong Yao, Colin Sumners, Stephen T, O'Rourke, and Chengwen Sun: Angiotensin II increases GABA B receptor expression in the nucleus tractus solitarius of rat
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00729.2007 [Abstract] [PDF]

Zlatina Naydenova, Jennifer B Rose, and Imogen R Coe: Inosine and equilibrative nucleoside transporter 2 (ENT2) contribute to hypoxic preconditioning in the murine cardiomyocyte cell line, HL-1
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00251.2007 [Abstract] [PDF]

Anna Csiszar, Nazar Labinskyy, Andrej Podlutsky, Pawel M Kaminski, Michael S. Wolin, Cuihua Zhang, Partha Mukhopadhyay, Pal Pacher, Furong Hu, Rafael de Cabo, Praveen Ballabh, and Zoltan I Ungvari: Vasoprotective Effects of Resveratrol and SIRT1: Attenuation of Cigarette Smoke-induced Oxidative Stress and Pro-inflammatory Phenotypic Alterations
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00235.2008 [Abstract] [PDF]

Wei Zhang and Sandor J Kovacs: The Diastatic Pressure-Volume Relationship Is Not the Same as the End-Diastolic Pressure-Volume Relationship
Am J Physiol Heart Circ Physiol (April 18, 2008). doi:10.1152/ajpheart.00200.2008 [Abstract]