AJP - Heart and Circulatory Physiology -- Table of Contents (November 1 2007, 293 [5])

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CALL FOR PAPERS:

Steven J. Miller, William C. Watson, Kimberly A. Kerr, Carlos A. Labarrere, Neal X. Chen, Mark A. Deeg, and Joseph L. Unthank: Development of progressive aortic vasculopathy in a rat model of aging
Am J Physiol Heart Circ Physiol 293: H2634-H2643, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00397.2007 [Abstract] [Full Text] [PDF]

William J. Welch, Kinjal Patel, Paul Modlinger, Margarida Mendonca, Noritaka Kawada, Kathryn Dennehy, Shakil Aslam, and Christopher S. Wilcox: Roles of vasoconstrictor prostaglandins, COX-1 and -2, and AT₁, AT₂, and TP receptors in a rat model of early 2K,1C hypertension
Am J Physiol Heart Circ Physiol 293: H2644-H2649, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00748.2007 [Abstract] [Full Text] [PDF]

Xavier Loyer, Patricia Oliviero, Thibaud Damy, Estelle Robidel, Françoise Marotte, Christophe Heymes, and Jane-Lise Samuel: Effects of sex differences on constitutive nitric oxide synthase expression and activity in response to pressure overload in rats
Am J Physiol Heart Circ Physiol 293: H2650-H2658, 2007. First published September 21, 2007; doi:10.1152/ajpheart.00883.2007 [Abstract] [Full Text] [PDF]

INVITED REVIEW:

Mirko Baruscotti and Richard B. Robinson: Electrophysiology and pacemaker function of the developing sinoatrial node
Am J Physiol Heart Circ Physiol 293: H2613-H2623, 2007. First published September 7, 2007; doi:10.1152/ajpheart.00750.2007 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Alden H. Harken: The world of inhibitory ${kappa}$ B
Am J Physiol Heart Circ Physiol 293: H2624-H2625, 2007. First published September 7, 2007; doi:10.1152/ajpheart.00923.2007 [Full Text] [PDF]

Joseph A. Palatinus and Robert G. Gourdie: Xin and the art of intercalated disk maintenance
Am J Physiol Heart Circ Physiol 293: H2626-H2628, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00954.2007 [Full Text] [PDF]

Dipak K. Das: Hydrogen sulfide preconditioning by garlic when it starts to smell
Am J Physiol Heart Circ Physiol 293: H2629-H2630, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00996.2007 [Full Text] [PDF]

Peter J. Schwartz and Emilio Vanoli: From exercise training to sudden death prevention via adrenergic receptors
Am J Physiol Heart Circ Physiol 293: H2631-H2633, 2007. First published September 28, 2007; doi:10.1152/ajpheart.01106.2007 [Full Text] [PDF]

TRANSLATIONAL PHYSIOLOGY:

Ines Pagel-Langenickel, Daniel R. Schwartz, Ross A. Arena, Diane C. Minerbi, D. Thor. Johnson, Myron A. Waclawiw, Richard O. Cannon, III, Robert S. Balaban, Dorothy J. Tripodi, and Michael N. Sack: A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in Type 2 diabetes mellitus
Am J Physiol Heart Circ Physiol 293: H2659-H2666, 2007. First published September 21, 2007; doi:10.1152/ajpheart.00782.2007 [Abstract] [Full Text] [PDF]

Charlotte Hwa and William C. Aird: The history of the capillary wall: doctors, discoveries, and debates
Am J Physiol Heart Circ Physiol 293: H2667-H2679, 2007. First published August 10, 2007; doi:10.1152/ajpheart.00704.2007 [Abstract] [Full Text] [PDF]

ARTICLES:

Elisabeth A. Gustafson-Wagner, Haley W. Sinn, Yen-Lin Chen, Da-Zhi Wang, Rebecca S. Reiter, Jenny L.-C. Lin, Baoli Yang, Roger A. Williamson, Ju Chen, Cheng-I. Lin, and Jim J.-C. Lin: Loss of mXin ${alpha}$ , an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects
Am J Physiol Heart Circ Physiol 293: H2680-H2692, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00806.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Shin Chet Chuah, Philip K. Moore, and Yi Zhun Zhu: S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathway
Am J Physiol Heart Circ Physiol 293: H2693-H2701, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00853.2007 [Abstract] [Full Text] [PDF]

Bethany J. Holycross, Monica Kukielka, Yoshinori Nishijima, Ruth A. Altschuld, Cynthia A. Carnes, and George E. Billman: Exercise training normalizes $beta$ -adrenoceptor expression in dogs susceptible to ventricular fibrillation
Am J Physiol Heart Circ Physiol 293: H2702-H2709, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00763.2007 [Abstract] [Full Text] [PDF]

Takao Muto, Norihiro Ueda, Tobias Opthof, Tomoko Ohkusa, Kohzo Nagata, Shinsuke Suzuki, Yukiomi Tsuji, Mitsuru Horiba, Jong-Kook Lee, Haruo Honjo, Kaichiro Kamiya, Itsuo Kodama, and Kenji Yasui: Aldosterone modulates I_f current through gene expression in cultured neonatal rat ventricular myocytes
Am J Physiol Heart Circ Physiol 293: H2710-H2718, 2007. First published July 20, 2007; doi:10.1152/ajpheart.01399.2006 [Abstract] [Full Text] [PDF]

Samuel J. Fountain, Alex Cheong, Jing Li, Naciye Y. Dondas, Fanning Zeng, Ian C. Wood, and David J. Beech: K_v1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress
Am J Physiol Heart Circ Physiol 293: H2719-H2725, 2007. First published July 27, 2007; doi:10.1152/ajpheart.00637.2007 [Abstract] [Full Text] [PDF]

Nithya Mariappan, Rajasekaran Namakkal Soorappan, Masudul Haque, Srinivas Sriramula, and Joseph Francis: TNF- ${alpha}$ -induced mitochondrial oxidative stress and cardiac dysfunction: restoration by superoxide dismutase mimetic Tempol
Am J Physiol Heart Circ Physiol 293: H2726-H2737, 2007. First published August 3, 2007; doi:10.1152/ajpheart.00376.2007 [Abstract] [Full Text] [PDF]

Wissam A. Jaber, Carolyn S. P. Lam, Donna M. Meyer, and Margaret M. Redfield: Revisiting methods for assessing and comparing left ventricular diastolic stiffness: impact of relaxation, external forces, hypertrophy, and comparators
Am J Physiol Heart Circ Physiol 293: H2738-H2746, 2007. First published August 10, 2007; doi:10.1152/ajpheart.00645.2007 [Abstract] [Full Text] [PDF]

Vincenzo Lionetti, Letizia Guiducci, Anca Simioniuc, Giovanni D. Aquaro, Claudia Simi, Daniele De Marchi, Silvia Burchielli, Lorenza Pratali, Marcello Piacenti, Massimo Lombardi, Piero Salvadori, Alessandro Pingitore, Danilo Neglia, and Fabio A. Recchia: Mismatch between uniform increase in cardiac glucose uptake and regional contractile dysfunction in pacing-induced heart failure
Am J Physiol Heart Circ Physiol 293: H2747-H2756, 2007. First published August 17, 2007; doi:10.1152/ajpheart.00592.2007 [Abstract] [Full Text] [PDF] [Supplemental Movies]

Rajesh B. Sekar, Eddy Kizana, Rachel R. Smith, Andreas S. Barth, Yibing Zhang, Eduardo Marbán, and Leslie Tung: Lentiviral vector-mediated expression of GFP or Kir2.1 alters the electrophysiology of neonatal rat ventricular myocytes without inducing cytotoxicity
Am J Physiol Heart Circ Physiol 293: H2757-H2770, 2007. First published August 3, 2007; doi:10.1152/ajpheart.00477.2007 [Abstract] [Full Text] [PDF]

P. Colli Franzone, L. F. Pavarino, S. Scacchi, and B. Taccardi: Monophasic action potentials generated by bidomain modeling as a tool for detecting cardiac repolarization times
Am J Physiol Heart Circ Physiol 293: H2771-H2785, 2007. First published August 17, 2007; doi:10.1152/ajpheart.00651.2007 [Abstract] [Full Text] [PDF]

Ronen Sumagin and Ingrid H. Sarelius: A role for ICAM-1 in maintenance of leukocyte-endothelial cell rolling interactions in inflamed arterioles
Am J Physiol Heart Circ Physiol 293: H2786-H2798, 2007. First published August 17, 2007; doi:10.1152/ajpheart.00720.2007 [Abstract] [Full Text] [PDF]

Heidi L. Lujan, Victoria J. Kramer, and Stephen E. DiCarlo: Sex influences the susceptibility to reperfusion-induced sustained ventricular tachycardia and $beta$ -adrenergic receptor blockade in conscious rats
Am J Physiol Heart Circ Physiol 293: H2799-H2808, 2007. First published July 13, 2007; doi:10.1152/ajpheart.00596.2007 [Abstract] [Full Text] [PDF]

He Gu, Min Lin, Jianyu Liu, David Gozal, Karie E. Scrogin, Robert Wurster, Mark W. Chapleau, Xiuying Ma, and Zixi (Jack) Cheng: Selective impairment of central mediation of baroreflex in anesthetized young adult Fischer 344 rats after chronic intermittent hypoxia
Am J Physiol Heart Circ Physiol 293: H2809-H2818, 2007. First published August 10, 2007; doi:10.1152/ajpheart.00358.2007 [Abstract] [Full Text] [PDF]

Makhosazane Zungu, Maria Pilar Alcolea, Francisco José García-Palmer, Martin E. Young, and M. Faadiel Essop: Genomic modulation of mitochondrial respiratory genes in the hypertrophied heart reflects adaptive changes in mitochondrial and contractile function
Am J Physiol Heart Circ Physiol 293: H2819-H2825, 2007. First published August 17, 2007; doi:10.1152/ajpheart.00806.2006 [Abstract] [Full Text] [PDF]

Leon P. Collis, Shekhar Srivastava, William A. Coetzee, and Michael Artman: $beta$ ₂-Adrenergic receptor agonists stimulate L-type calcium current independent of PKA in newborn rabbit ventricular myocytes
Am J Physiol Heart Circ Physiol 293: H2826-H2835, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00101.2007 [Abstract] [Full Text] [PDF]

Wen Qiang Chen, Lei Zhang, Yun Fang Liu, Liang Chen, Xiao Ping Ji, Mei Zhang, Yu Xia Zhao, Gui Hua Yao, Cheng Zhang, Xing Li Wang, and Yun Zhang: Prediction of atherosclerotic plaque ruptures with high-frequency ultrasound imaging and serum inflammatory markers
Am J Physiol Heart Circ Physiol 293: H2836-H2844, 2007. First published August 17, 2007; doi:10.1152/ajpheart.00472.2007 [Abstract] [Full Text] [PDF]

Rong Jiang, Amanda Zatta, Hajime Kin, Ningping Wang, James G. Reeves, James Mykytenko, Jeremiah Deneve, Zhi-Qing Zhao, Robert A. Guyton, and Jakob Vinten-Johansen: PAR-2 activation at the time of reperfusion salvages myocardium via an ERK1/2 pathway in in vivo rat hearts
Am J Physiol Heart Circ Physiol 293: H2845-H2852, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00209.2007 [Abstract] [Full Text] [PDF]

Jeffrey A. LaMack and Morton H. Friedman: Individual and combined effects of shear stress magnitude and spatial gradient on endothelial cell gene expression
Am J Physiol Heart Circ Physiol 293: H2853-H2859, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00244.2007 [Abstract] [Full Text] [PDF]

Darren J. Kelly, Yuan Zhang, Kim Connelly, Alison J. Cox, Jennifer Martin, Henry Krum, and Richard E. Gilbert: Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy
Am J Physiol Heart Circ Physiol 293: H2860-H2869, 2007. First published August 24, 2007; doi:10.1152/ajpheart.01167.2006 [Abstract] [Full Text] [PDF]

Krystyna M. Shioura, David L. Geenen, and Paul H. Goldspink: Assessment of cardiac function with the pressure-volume conductance system following myocardial infarction in mice
Am J Physiol Heart Circ Physiol 293: H2870-H2877, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00585.2007 [Abstract] [Full Text] [PDF]

Rita K. Upmacis, Mark J. Crabtree, Ruba S. Deeb, Hao Shen, Paul B. Lane, Lea Esther S. Benguigui, Nobuyo Maeda, David P. Hajjar, and Steven S. Gross: Profound biopterin oxidation and protein tyrosine nitration in tissues of ApoE-null mice on an atherogenic diet: contribution of inducible nitric oxide synthase
Am J Physiol Heart Circ Physiol 293: H2878-H2887, 2007. First published August 31, 2007; doi:10.1152/ajpheart.01144.2006 [Abstract] [Full Text] [PDF]

Xiao-Hui Zhang, Gui-Rong Li, and Jean-Pierre Bourreau: The effect of adrenomedullin on the L-type calcium current in myocytes from septic shock rats: signaling pathway
Am J Physiol Heart Circ Physiol 293: H2888-H2893, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00312.2007 [Abstract] [Full Text] [PDF]

Louise Østergaard, Edgaras Stankevicius, Malene R. Andersen, Yvonne Eskildsen-Helmond, Thomas Ledet, Michael J. Mulvany, and Ulf Simonsen: Diminished NO release in chronic hypoxic human endothelial cells
Am J Physiol Heart Circ Physiol 293: H2894-H2903, 2007. First published August 24, 2007; doi:10.1152/ajpheart.01230.2006 [Abstract] [Full Text] [PDF]

Alan R. Burns, Zhilan Zheng, Said H. Soubra, Jie Chen, and Rolando E. Rumbaut: Transendothelial flow inhibits neutrophil transmigration through a nitric oxide-dependent mechanism: potential role for cleft shear stress
Am J Physiol Heart Circ Physiol 293: H2904-H2910, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00871.2007 [Abstract] [Full Text] [PDF]

Kyan J. Allahdadi, Benjimen R. Walker, and Nancy L. Kanagy: ROK contribution to endothelin-mediated contraction in aorta and mesenteric arteries following intermittent hypoxia/hypercapnia in rats
Am J Physiol Heart Circ Physiol 293: H2911-H2918, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00217.2007 [Abstract] [Full Text] [PDF]

Sanjoy Ghosh, Elizabeth M. Novak, and Sheila M. Innis: Cardiac proinflammatory pathways are altered with different dietary n-6 linoleic to n-3 ${alpha}$ -linolenic acid ratios in normal, fat-fed pigs
Am J Physiol Heart Circ Physiol 293: H2919-H2927, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00324.2007 [Abstract] [Full Text] [PDF]

Kathryn L. Walker, Natasha R. Saunders, Dennis Jensen, Jennifer L. Kuk, Suzi-Lai Wong, Kyra E. Pyke, Erin M. Dwyer, and Michael E. Tschakovsky: Do vasoregulatory mechanisms in exercising human muscle compensate for changes in arterial perfusion pressure?
Am J Physiol Heart Circ Physiol 293: H2928-H2936, 2007. First published August 17, 2007; doi:10.1152/ajpheart.00576.2007 [Abstract] [Full Text] [PDF]

Terrence E. Sweeney, Pooneh Bagher, Jocelyn Bailey, Salvatore J. Cherra, 3rd, Frank N. Grisafi, Eric M. Pauli, Kristin Riley, and Sarita Soares: Intravascular pressure and diameter profile of the utero-ovarian resistance artery network: estrous cycle-dependent modulation of resistance artery tone
Am J Physiol Heart Circ Physiol 293: H2937-H2944, 2007. First published August 17, 2007; doi:10.1152/ajpheart.01019.2006 [Abstract] [Full Text] [PDF]

Edward O. McFalls, Rosemary F. Kelly, Qingsong Hu, Abdul Mansoor, Joseph Lee, Michael Kuskowski, Joseph Sikora, Herbert B. Ward, and Jianyi Zhang: The energetic state within hibernating myocardium is normal during dobutamine despite inhibition of ATP-dependent potassium channel opening with glibenclamide
Am J Physiol Heart Circ Physiol 293: H2945-H2951, 2007. First published August 24, 2007; doi:10.1152/ajpheart.00012.2007 [Abstract] [Full Text] [PDF]

Xiangbin Xu, Jinjiang Pang, Hongchao Yin, Meixiu Li, Wei Hao, Chen Chen, and Ji-Min Cao: Hexarelin suppresses cardiac fibroblast proliferation and collagen synthesis in rat
Am J Physiol Heart Circ Physiol 293: H2952-H2958, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00004.2007 [Abstract] [Full Text] [PDF]

Yunlong Huo, Thomas Wischgoll, and Ghassan S. Kassab: Flow patterns in three-dimensional porcine epicardial coronary arterial tree
Am J Physiol Heart Circ Physiol 293: H2959-H2970, 2007. First published September 7, 2007; doi:10.1152/ajpheart.00586.2007 [Abstract] [Full Text] [PDF]

Carmen M. Troncoso Brindeiro, Ana Q. da Silva, Kyan J. Allahdadi, Victoria Youngblood, and Nancy L. Kanagy: Reactive oxygen species contribute to sleep apnea-induced hypertension in rats
Am J Physiol Heart Circ Physiol 293: H2971-H2976, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00219.2007 [Abstract] [Full Text] [PDF]

Zoë L. S. Brookes, Emily N. Stedman, Remo Guerrini, Bethan K. Lawton, Girolamo Calo, and David G. Lambert: Proinflammatory and vasodilator effects of nociceptin/orphanin FQ in the rat mesenteric microcirculation are mediated by histamine
Am J Physiol Heart Circ Physiol 293: H2977-H2985, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00448.2007 [Abstract] [Full Text] [PDF]

Yi-Mei Du and Richard D. Nathan: Simulated ischemia enhances L-type calcium current in pacemaker cells isolated from the rabbit sinoatrial node
Am J Physiol Heart Circ Physiol 293: H2986-H2994, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00491.2007 [Abstract] [Full Text] [PDF]

Angela E. Kindig, Shawn G. Hayes, and Marc P. Kaufman: Blockade of purinergic 2 receptors attenuates the mechanoreceptor component of the exercise pressor reflex
Am J Physiol Heart Circ Physiol 293: H2995-H3000, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00743.2007 [Abstract] [Full Text] [PDF]

Egbert Bisping, Gero Tenderich, Paul Barckhausen, Burkhard Stumme, Sebastian Bruns, Dirk von Lewinski, and Burkert Pieske: Atrial myocardium is the predominant inotropic target of adrenomedullin in the human heart
Am J Physiol Heart Circ Physiol 293: H3001-H3007, 2007. First published August 31, 2007; doi:10.1152/ajpheart.01276.2006 [Abstract] [Full Text] [PDF]

A. M. D. Gonzalez, J. C. Osorio, C. Manlhiot, D. Gruber, S. Homma, and S. Mital: Hypertrophy signaling during peripartum cardiac remodeling
Am J Physiol Heart Circ Physiol 293: H3008-H3013, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00401.2007 [Abstract] [Full Text] [PDF]

Cécile Moro, Marie-Gabrielle Jouan, Andry Rakotovao, Marie-Claire Toufektsian, Olivier Ormezzano, Norbert Nagy, Arpad Tosaki, Joël de Leiris, and François Boucher: Delayed expression of cytokines after reperfused myocardial infarction: possible trigger for cardiac dysfunction and ventricular remodeling
Am J Physiol Heart Circ Physiol 293: H3014-H3019, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00797.2007 [Abstract] [Full Text] [PDF]

Esben Thyssen Vestergaard, Niels Holmark Andersen, Troels Krarup Hansen, Lars Melholt Rasmussen, Niels Moller, Keld E. Sorensen, Erik Sloth, and Jens Otto Lunde Jorgensen: Cardiovascular effects of intravenous ghrelin infusion in healthy young men
Am J Physiol Heart Circ Physiol 293: H3020-H3026, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00496.2007 [Abstract] [Full Text] [PDF]

Renaud Tamisier, Brian E. Hunt, Geoffrey S. Gilmartin, Mathew Curley, Amit Anand, and J. Woodrow Weiss: Hemodynamics and muscle sympathetic nerve activity after 8 h of sustained hypoxia in healthy humans
Am J Physiol Heart Circ Physiol 293: H3027-H3035, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00277.2007 [Abstract] [Full Text] [PDF]

Jonna R. Terkildsen, Edmund J. Crampin, and Nicolas P. Smith: The balance between inactivation and activation of the Na⁺-K⁺ pump underlies the triphasic accumulation of extracellular K⁺ during myocardial ischemia
Am J Physiol Heart Circ Physiol 293: H3036-H3045, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00771.2007 [Abstract] [Full Text] [PDF] [Supplemental Information]

Lauren Johnson, Hyung Kook Kim, Masaki Tanabe, John Gorcsan, David Schwartzman, Sanjeev G. Shroff, and Michael R. Pinsky: Differential effects of left ventricular pacing sites in an acute canine model of contraction dyssynchrony
Am J Physiol Heart Circ Physiol 293: H3046-H3055, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00728.2007 [Abstract] [Full Text] [PDF]

Jian-Bing Shen, Robin Shutt, Achilles Pappano, and Bruce T. Liang: Characterization and mechanism of P2X receptor-mediated increase in cardiac myocyte contractility
Am J Physiol Heart Circ Physiol 293: H3056-H3062, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00515.2007 [Abstract] [Full Text] [PDF]

Siva Bhashyam, Pratik Parikh, Hakki Bolukoglu, Alexander H. Shannon, James H. Porter, You-Tang Shen, and Richard P. Shannon: Aging is associated with myocardial insulin resistance and mitochondrial dysfunction
Am J Physiol Heart Circ Physiol 293: H3063-H3071, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00163.2007 [Abstract] [Full Text] [PDF]

David M. Harris, Heather I. Cohn, Stéphanie Pesant, Rui-Hai Zhou, and Andrea D. Eckhart: Vascular smooth muscle G_q signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension
Am J Physiol Heart Circ Physiol 293: H3072-H3079, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00880.2007 [Abstract] [Full Text] [PDF]

Tian Xia, Christiana Dimitropoulou, Jingmin Zeng, Galina N. Antonova, Connie Snead, Richard C. Venema, David Fulton, Shuibing Qian, Cam Patterson, Andreas Papapetropoulos, and John D. Catravas: Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase
Am J Physiol Heart Circ Physiol 293: H3080-H3087, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00579.2007 [Abstract] [Full Text] [PDF]

Carlos Bechara, Xinwen Wang, Hong Chai, Peter H. Lin, Qizhi Yao, and Changyi Chen: Growth-related oncogene- ${alpha}$ induces endothelial dysfunction through oxidative stress and downregulation of eNOS in porcine coronary arteries
Am J Physiol Heart Circ Physiol 293: H3088-H3095, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00473.2007 [Abstract] [Full Text] [PDF]

Erika Toth, Anita Racz, Janos Toth, Pawel M. Kaminski, Michael S. Wolin, Zsolt Bagi, and Akos Koller: Contribution of polyol pathway to arteriolar dysfunction in hyperglycemia. Role of oxidative stress, reduced NO, and enhanced PGH₂/TXA₂ mediation
Am J Physiol Heart Circ Physiol 293: H3096-H3104, 2007. First published September 14, 2007; doi:10.1152/ajpheart.01335.2006 [Abstract] [Full Text] [PDF]

Changdong Yan, An Huang, Gabor Kaley, and Dong Sun: Chronic high blood flow potentiates shear stress-induced release of NO in arteries of aged rats
Am J Physiol Heart Circ Physiol 293: H3105-H3110, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00627.2007 [Abstract] [Full Text] [PDF]

Samir Turakhia, C. D. Venkatakrishnan, Kathy Dunsmore, Hector Wong, Periannan Kuppusamy, Jay L. Zweier, and Govindasamy Ilangovan: Doxorubicin-induced cardiotoxicity: direct correlation of cardiac fibroblast and H9c2 cell survival and aconitase activity with heat shock protein 27
Am J Physiol Heart Circ Physiol 293: H3111-H3121, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00328.2007 [Abstract] [Full Text] [PDF]

Scott M. MacDonnell, Hajime Kubo, David M. Harris, Xiongwen Chen, Remus Berretta, Mary F. Barbe, Stephen Kolwicz, Patricia O. Reger, Andrea Eckhart, Brian F. Renna, Walter J. Koch, Steven R. Houser, and Joseph R. Libonati: Calcineurin inhibition normalizes $beta$ -adrenergic responsiveness in the spontaneously hypertensive rat
Am J Physiol Heart Circ Physiol 293: H3122-H3129, 2007. First published September 7, 2007; doi:10.1152/ajpheart.00687.2007 [Abstract] [Full Text] [PDF]

Alkiviadis Tsamis and Nikos Stergiopulos: Arterial remodeling in response to hypertension using a constituent-based model
Am J Physiol Heart Circ Physiol 293: H3130-H3139, 2007. First published September 7, 2007; doi:10.1152/ajpheart.00684.2007 [Abstract] [Full Text] [PDF]

Steven N. Mink, Zhao-Qin Cheng, Ratna Bose, Hans Jacobs, Krika Kasian, Diane E. Roberts, Luis E. Santos-Martinez, and R. Bruce Light: Lysozyme, a mediator of sepsis, impairs the cardiac neural adrenergic response by nonendothelial release of NO and inhibitory G protein signaling
Am J Physiol Heart Circ Physiol 293: H3140-H3149, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00502.2007 [Abstract] [Full Text] [PDF]

Jianqing Zhang, Norman Honbo, Edward J. Goetzl, Kanu Chatterjee, Joel S. Karliner, and Mary O. Gray: Signals from type 1 sphingosine 1-phosphate receptors enhance adult mouse cardiac myocyte survival during hypoxia
Am J Physiol Heart Circ Physiol 293: H3150-H3158, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00587.2006 [Abstract] [Full Text] [PDF]

Claire Demiot, Françoise Dignat-George, Jacques-Olivier Fortrat, Florence Sabatier, Claude Gharib, Irina Larina, Guillemette Gauquelin-Koch, Richard Hughson, and Marc-Antoine Custaud: WISE 2005: chronic bed rest impairs microcirculatory endothelium in women
Am J Physiol Heart Circ Physiol 293: H3159-H3164, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00591.2007 [Abstract] [Full Text] [PDF]

Uwe Kirchhefer, Jan Klimas, Hideo A. Baba, Igor B. Buchwalow, Larissa Fabritz, Marion Hüls, Marek Matus, Frank U. Müller, Wilhelm Schmitz, and Joachim Neumann: Triadin is a critical determinant of cellular Ca cycling and contractility in the heart
Am J Physiol Heart Circ Physiol 293: H3165-H3174, 2007. First published September 21, 2007; doi:10.1152/ajpheart.00799.2007 [Abstract] [Full Text] [PDF]

Michal Odermarsky, Anita Nilsson, Åke Lernmark, Sture Sjöblad, and Petru Liuba: Atherogenic vascular and lipid phenotypes in young patients with Type 1 diabetes are associated with diabetes high-risk HLA genotype
Am J Physiol Heart Circ Physiol 293: H3175-H3179, 2007. First published September 28, 2007; doi:10.1152/ajpheart.00795.2007 [Abstract] [Full Text] [PDF]

Kevin S. Heffernan, Christopher A. Fahs, Kevin K. Shinsako, Sae Young Jae, and Bo Fernhall: Heart rate recovery and heart rate complexity following resistance exercise training and detraining in young men
Am J Physiol Heart Circ Physiol 293: H3180-H3186, 2007. First published September 21, 2007; doi:10.1152/ajpheart.00648.2007 [Abstract] [Full Text] [PDF]

Gary J. Hodges, Wojciech A. Kosiba, Kun Zhao, Guy E. Alvarez, and John M. Johnson: The role of baseline in the cutaneous vasoconstrictor responses during combined local and whole body cooling in humans
Am J Physiol Heart Circ Physiol 293: H3187-H3192, 2007. First published September 28, 2007; doi:10.1152/ajpheart.00815.2007 [Abstract] [Full Text] [PDF]

Alie Kanu and Charles W. Leffler: Carbon monoxide and Ca²⁺-activated K⁺ channels in cerebral arteriolar responses to glutamate and hypoxia in newborn pigs
Am J Physiol Heart Circ Physiol 293: H3193-H3200, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00274.2007 [Abstract] [Full Text] [PDF]

Ivor J. Benjamin, Yiru Guo, Sathyanarayanan Srinivasan, Sihem Boudina, Ryan P. Taylor, Namakkal S. Rajasekaran, Roberta Gottlieb, Eric F. Wawrousek, E. Dale Abel, and Roberto Bolli: CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice
Am J Physiol Heart Circ Physiol 293: H3201-H3209, 2007. First published September 14, 2007; doi:10.1152/ajpheart.01363.2006 [Abstract] [Full Text] [PDF]

Jean-Francois Légaré, Adam Oxner, Olivier Heimrath, Tanya Myers, and R. William Currie: Heat shock treatment results in increased recruitment of labeled PMN following myocardial infarction
Am J Physiol Heart Circ Physiol 293: H3210-H3215, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00773.2007 [Abstract] [Full Text] [PDF]

LETTERS TO THE EDITOR:

Craig Lygate: Letter to the editor: Infarct size measurements are critically important when comparing interventions affecting ventricular remodeling
Am J Physiol Heart Circ Physiol 293: H3221-H3221, 2007; doi:10.1152/ajpheart.00908.2007 [Full Text] [PDF]

Dinender K. Singla, Gary E. Lyon, and Timothy J. Kamp: Reply to "Letter to the editor: Infarct size measurements are critically important when comparing interventions affecting ventricular remodeling"
Am J Physiol Heart Circ Physiol 293: H3222-H3222, 2007; doi:10.1152/ajpheart.00978.2007 [Full Text] [PDF]

Paul A. J. Krijnen and Hans W. M. Niessen: The antiapoptotic protein clusterin protects cardiomyocytes against ischemia-induced cell death
Am J Physiol Heart Circ Physiol 293: H3223-H3223, 2007; doi:10.1152/ajpheart.00964.2007 [Full Text] [PDF]

Dinender K. Singla: Reply to "The antiapoptotic protein clusterin protects cardiomyocytes against ischemia-induced cell death"
Am J Physiol Heart Circ Physiol 293: H3224-H3224, 2007; doi:10.1152/ajpheart.01096.2007 [Full Text] [PDF]

REPORTS:

James S. Swaney, Hemal H. Patel, Utako Yokoyama, N. Chin Lai, Matthew Spellman, Paul A. Insel, and David M. Roth: Adenylyl cyclase activity and function are decreased in rat cardiac fibroblasts after myocardial infarction
Am J Physiol Heart Circ Physiol 293: H3216-H3220, 2007. First published September 14, 2007; doi:10.1152/ajpheart.00739.2007 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: TGF-β₁ immunohistochemical staining in a rabbit vein graft following exposure to reduced wall stress. In contrast to vein grafts exposed to normal wall stress, minimal TGF-β₁ staining or adventitial myofibroblasts are noted in the remodeling adventitia. From: Jiang Z, Yu P, Tao M, Fernandez C, Ifantides C, Moloye O, Schultz GS, Ozaki CK, Berceli SA. “TGF-β- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling.” Am J Physiol Heart Circ Physiol 293: H482-H488, 2007.