CALL FOR PAPERS:

Dan Ye, Wei Zhou, Tong Lu, Setti G. Jagadeesh, John R. Falck, and Hon-Chi Lee

Mechanism of rat mesenteric arterial K_ATP channel activation by 14,15-epoxyeicosatrienoic acid
Am J Physiol Heart Circ Physiol 290: H1326-H1336, 2006; doi:10.1152/ajpheart.00318.2005 [Abstract] [Full Text] [PDF]  

Kristina M. Fetalvero, Maureen Shyu, Athena P. Nomikos, Yuh-Fang Chiu, Robert J. Wagner, Richard J. Powell, John Hwa, and Kathleen A. Martin

The prostacyclin receptor induces human vascular smooth muscle cell differentiation via the protein kinase A pathway
Am J Physiol Heart Circ Physiol 290: H1337-H1346, 2006. First published January 6, 2006; doi:10.1152/ajpheart.00936.2005 [Abstract] [Full Text] [PDF]  

Jeremy Bellien, Robinson Joannides, Michele Iacob, Philippe Arnaud, and Christian Thuillez

Evidence for a basal release of a cytochrome-related endothelium-derived hyperpolarizing factor in the radial artery in humans
Am J Physiol Heart Circ Physiol 290: H1347-H1352, 2006. First published December 9, 2005; doi:10.1152/ajpheart.01079.2005 [Abstract] [Full Text] [PDF]  

Michael J. Wacker, Shaun R. Best, Lisa M. Kosloski, Christopher J. Stachura, Rory L. Smoot, Charles B. Porter, and James A. Orr

Thromboxane A₂-induced arrhythmias in the anesthetized rabbit
Am J Physiol Heart Circ Physiol 290: H1353-H1361, 2006. First published December 9, 2005; doi:10.1152/ajpheart.00930.2005 [Abstract] [Full Text] [PDF]  

Tao-Sheng Li, Akira Furutani, Masaya Takahashi, Mako Ohshima, Shu-Lan Qin, Toshiro Kobayashi, Hiroshi Ito, and Kimikazu Hamano

Impaired potency of bone marrow mononuclear cells for inducing therapeutic angiogenesis in obese diabetic rats
Am J Physiol Heart Circ Physiol 290: H1362-H1369, 2006. First published October 14, 2005; doi:10.1152/ajpheart.00766.2005 [Abstract] [Full Text] [PDF]  

Vincent F. M. Segers, Ivan Van Riet, Luc J. Andries, Katrien Lemmens, Marc J. Demolder, Ann J. M. L. De Becker, Mark M. Kockx, and Gilles W. De Keulenaer

Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms
Am J Physiol Heart Circ Physiol 290: H1370-H1377, 2006. First published October 21, 2005; doi:10.1152/ajpheart.00523.2005 [Abstract] [Full Text] [PDF]  

Stephen R. Thom, Veena M. Bhopale, Omaida C. Velazquez, Lee J. Goldstein, Lynne H. Thom, and Donald G. Buerk

Stem cell mobilization by hyperbaric oxygen
Am J Physiol Heart Circ Physiol 290: H1378-H1386, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00888.2005 [Abstract] [Full Text] [PDF]  

David A. Klibansky, Andrew Chin, Inga J. Duignan, and Jay M. Edelberg

Synergistic targeting with bone marrow-derived cells and PDGF improves diabetic vascular function
Am J Physiol Heart Circ Physiol 290: H1387-H1392, 2006. First published December 9, 2005; doi:10.1152/ajpheart.00652.2005 [Abstract] [Full Text] [PDF]  

Xiaohong Wang, Qingsong Hu, Abdul Mansoor, Joseph Lee, Zongli Wang, TeChung Lee, Arthur H. L. From, and Jianyi Zhang

Bioenergetic and functional consequences of stem cell-based VEGF delivery in pressure-overloaded swine hearts
Am J Physiol Heart Circ Physiol 290: H1393-H1405, 2006. First published December 30, 2005; doi:10.1152/ajpheart.00871.2005 [Abstract] [Full Text] [PDF]  

INVITED REVIEW:

Masahiko Hoshijima

Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures
Am J Physiol Heart Circ Physiol 290: H1313-H1325, 2006; doi:10.1152/ajpheart.00816.2005 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Don D. Sheriff

Baroreflex resetting during exercise: mechanisms and meaning
Am J Physiol Heart Circ Physiol 290: H1406-H1407, 2006; doi:10.1152/ajpheart.01275.2005 [Full Text] [PDF]  

Sven T. Pleger and Walter J. Koch

The yin and yang of increased -adrenergic signaling: ₁-adrenergic genetic polymorphism and protection against acute myocardial ischemic injury
Am J Physiol Heart Circ Physiol 290: H1408-H1409, 2006; doi:10.1152/ajpheart.01156.2005 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Marie-Claire Toufektsian, Zequan Yang, Konkal M. Prasad, Lutgart Overbergh, Susan I. Ramos, Chantal Mathieu, Joel Linden, and Brent A. French

Stimulation of A_2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle
Am J Physiol Heart Circ Physiol 290: H1410-H1418, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00860.2005 [Abstract] [Full Text] [PDF]  

ARTICLES:

Masashi Ichinose, Mitsuru Saito, Narihiko Kondo, and Takeshi Nishiyasu

Time-dependent modulation of arterial baroreflex control of muscle sympathetic nerve activity during isometric exercise in humans
Am J Physiol Heart Circ Physiol 290: H1419-H1426, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00847.2005 [Abstract] [Full Text] [PDF]  

Shahab A. Akhter, Karen M. D'Souza, Natalia N. Petrashevskaya, Jeanne Mialet-Perez, and Stephen B. Liggett

Myocardial ₁-adrenergic receptor polymorphisms affect functional recovery after ischemic injury
Am J Physiol Heart Circ Physiol 290: H1427-H1432, 2006; doi:10.1152/ajpheart.00908.2005 [Abstract] [Full Text] [PDF]  

Jacqueline M. Cale and Ian M. Bird

Dissociation of endothelial nitric oxide synthase phosphorylation and activity in uterine artery endothelial cells
Am J Physiol Heart Circ Physiol 290: H1433-H1445, 2006. First published November 4, 2005; doi:10.1152/ajpheart.00942.2005 [Abstract] [Full Text] [PDF]  

Kenneth S. Dyson, J. Kevin Shoemaker, and Richard L. Hughson

Effect of acute sympathetic nervous system activation on flow-mediated dilation of brachial artery
Am J Physiol Heart Circ Physiol 290: H1446-H1453, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00771.2005 [Abstract] [Full Text] [PDF]  

Zoran B. Popovic, Anand Prasad, Mario J. Garcia, Armin Arbab-Zadeh, Allen Borowski, Erika Dijk, Neil L. Greenberg, Benjamin D. Levine, and James D. Thomas

Relationship among diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness
Am J Physiol Heart Circ Physiol 290: H1454-H1459, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00902.2005 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

Ellen Berggreen and Helge Wiig

Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion
Am J Physiol Heart Circ Physiol 290: H1460-H1468, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00887.2005 [Abstract] [Full Text] [PDF]  

Amy R. Lankford, Jiang-Ning Yang, Roselyn Rose'Meyer, Brent A. French, G. Paul Matherne, Bertil B. Fredholm, and Zequan Yang

Effect of modulating cardiac A₁ adenosine receptor expression on protection with ischemic preconditioning
Am J Physiol Heart Circ Physiol 290: H1469-H1473, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00181.2005 [Abstract] [Full Text] [PDF]  

T. E. Claessens, D. Georgakopoulos, M. Afanasyeva, S. J. Vermeersch, H. D. Millar, N. Stergiopulos, N. Westerhof, P. R. Verdonck, and P. Segers

Nonlinear isochrones in murine left ventricular pressure-volume loops: how well does the time-varying elastance concept hold?
Am J Physiol Heart Circ Physiol 290: H1474-H1483, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00663.2005 [Abstract] [Full Text] [PDF]  

Kazuhiro Kaneko, Yoshikazu Yonemitsu, Takaaki Fujii, Mitsuho Onimaru, Chen-Hao Jin, Makoto Inoue, Mamoru Hasegawa, Toshihiro Onohara, Yoshihiko Maehara, and Katsuo Sueishi

A free radical scavenger but not FGF-2-mediated angiogenic therapy rescues myonephropathic metabolic syndrome in severe hindlimb ischemia
Am J Physiol Heart Circ Physiol 290: H1484-H1492, 2006. First published November 18, 2005; doi:10.1152/ajpheart.01006.2005 [Abstract] [Full Text] [PDF]  

Rumi Maruyama, Genzou Takemura, Noritsugu Tohse, Tomoko Ohkusa, Yasuhiro Ikeda, Kunihiko Tsuchiya, Shinya Minatoguchi, Masunori Matsuzaki, Takako Fujiwara, and Hisayoshi Fujiwara

Synchronous progression of calcium transient-dependent beating and sarcomere destruction in apoptotic adult cardiomyocytes
Am J Physiol Heart Circ Physiol 290: H1493-H1502, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00669.2005 [Abstract] [Full Text] [PDF] [Supplemental Videos]  

Jasmina Varagic, Edward D. Frohlich, Javier Díez, Dinko Susic, Jwari Ahn, Arantxa González, and Begoña López

Myocardial fibrosis, impaired coronary hemodynamics, and biventricular dysfunction in salt-loaded SHR
Am J Physiol Heart Circ Physiol 290: H1503-H1509, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00970.2005 [Abstract] [Full Text] [PDF]  

Yuri V. Bobryshev, Reginald S. A. Lord, and Dinh Tran

Chlamydia pneumoniae in foci of "early" calcification of the tunica media in arteriosclerotic arteries: an incidental presence?
Am J Physiol Heart Circ Physiol 290: H1510-H1519, 2006. First published November 4, 2005; doi:10.1152/ajpheart.01055.2005 [Abstract] [Full Text] [PDF]  

Matthew P. Burnham, Ian T. Johnson, and Arthur H. Weston

Reduced Ca²⁺-dependent activation of large-conductance Ca²⁺-activated K⁺ channels from arteries of Type 2 diabetic Zucker diabetic fatty rats
Am J Physiol Heart Circ Physiol 290: H1520-H1527, 2006. First published November 4, 2005; doi:10.1152/ajpheart.00827.2005 [Abstract] [Full Text] [PDF]  

C. Tji-Joong Gan, Jan-Willem Lankhaar, J. Tim Marcus, Nico Westerhof, Koen M. Marques, Jean G. F. Bronzwaer, Anco Boonstra, Pieter E. Postmus, and Anton Vonk-Noordegraaf

Impaired left ventricular filling due to right-to-left ventricular interaction in patients with pulmonary arterial hypertension
Am J Physiol Heart Circ Physiol 290: H1528-H1533, 2006. First published November 11, 2005; doi:10.1152/ajpheart.01031.2005 [Abstract] [Full Text] [PDF]  

Carlos Labat, Roberto S. A. Cunha, Pascal Challande, Michel E. Safar, and Patrick Lacolley

Respective contribution of age, mean arterial pressure, and body weight on central arterial distensibility in SHR
Am J Physiol Heart Circ Physiol 290: H1534-H1539, 2006. First published October 21, 2005; doi:10.1152/ajpheart.00742.2005 [Abstract] [Full Text] [PDF]  

David Jegger, Xavier Jeanrenaud, Mohammad Nasratullah, Pierre-Guy Chassot, Ajit Mallik, Hendrik Tevaearai, Ludwig K. von Segesser, Patrick Segers, and Nikolaos Stergiopulos

Noninvasive Doppler-derived myocardial performance index in rats with myocardial infarction: validation and correlation by conductance catheter
Am J Physiol Heart Circ Physiol 290: H1540-H1548, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00935.2005 [Abstract] [Full Text] [PDF]  

Mariannick Marcil, Karine Bourduas, Alexis Ascah, and Yan Burelle

Exercise training induces respiratory substrate-specific decrease in Ca²⁺-induced permeability transition pore opening in heart mitochondria
Am J Physiol Heart Circ Physiol 290: H1549-H1557, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00913.2005 [Abstract] [Full Text] [PDF]  

Jenny Susana Choy, Quang Dang, Sabee Molloi, and Ghassan S. Kassab

Nonuniformity of axial and circumferential remodeling of large coronary veins in response to ligation
Am J Physiol Heart Circ Physiol 290: H1558-H1565, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00928.2005 [Abstract] [Full Text] [PDF]  

Susan E. Howlett, Scott A. Grandy, and Gregory R. Ferrier

Calcium spark properties in ventricular myocytes are altered in aged mice
Am J Physiol Heart Circ Physiol 290: H1566-H1574, 2006. First published December 3, 2005; doi:10.1152/ajpheart.00686.2005 [Abstract] [Full Text] [PDF]  

Jun Chen, Xuan Huang, Dorota Halicka, Sergey Brodsky, Ari Avram, Jonathan Eskander, Noah A. Bloomgarden, Zbigniew Darzynkiewicz, and Michael S. Goligorsky

Contribution of p16^INK4a and p21^CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53
Am J Physiol Heart Circ Physiol 290: H1575-H1586, 2006. First published October 21, 2005; doi:10.1152/ajpheart.00364.2005 [Abstract] [Full Text] [PDF]  

Aaron K. Olson, Kristin N. Protheroe, Jeffrey L. Segar, and Thomas D. Scholz

Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart
Am J Physiol Heart Circ Physiol 290: H1587-H1595, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00984.2005 [Abstract] [Full Text] [PDF]  

Jill N. Cook, Allison E. DeVan, Jessica L. Schleifer, Maria M. Anton, Miriam Y. Cortez-Cooper, and Hirofumi Tanaka

Arterial compliance of rowers: implications for combined aerobic and strength training on arterial elasticity
Am J Physiol Heart Circ Physiol 290: H1596-H1600, 2006. First published November 11, 2005; doi:10.1152/ajpheart.01054.2005 [Abstract] [Full Text] [PDF]  

Jian Cui, Mithra Sathishkumar, Thad E. Wilson, Manabu Shibasaki, Scott L. Davis, and Craig G. Crandall

Spectral characteristics of skin sympathetic nerve activity in heat-stressed humans
Am J Physiol Heart Circ Physiol 290: H1601-H1609, 2006. First published November 23, 2005; doi:10.1152/ajpheart.00025.2005 [Abstract] [Full Text] [PDF]  

K. J. Milne, D. B. Thorp, C. W. J. Melling, and E. G. Noble

Castration inhibits exercise-induced accumulation of Hsp70 in male rodent hearts
Am J Physiol Heart Circ Physiol 290: H1610-H1616, 2006. First published November 4, 2005; doi:10.1152/ajpheart.01103.2004 [Abstract] [Full Text] [PDF]  

Erion Qamirani, Habib M. Razavi, Xin Wu, Michael J. Davis, Lih Kuo, and Travis W. Hein

Sodium azide dilates coronary arterioles via activation of inward rectifier K⁺ channels and Na⁺-K⁺-ATPase
Am J Physiol Heart Circ Physiol 290: H1617-H1623, 2006. First published December 3, 2005; doi:10.1152/ajpheart.00746.2005 [Abstract] [Full Text] [PDF]  

Mimi Sohn, Yan Tan, Bing Wang, Richard L. Klein, Maria Trojanowska, and Ayad A. Jaffa

Mechanisms of low-density lipoprotein-induced expression of connective tissue growth factor in human aortic endothelial cells
Am J Physiol Heart Circ Physiol 290: H1624-H1634, 2006. First published November 4, 2005; doi:10.1152/ajpheart.01233.2004 [Abstract] [Full Text] [PDF]  

Tue E. H. Christoffersen, Mark Aplin, Claes C. Strom, Soren P. Sheikh, Ole Skott, Peter K. Busk, Stig Haunso, and Lars B. Nielsen

Increased natriuretic peptide receptor A and C gene expression in rats with pressure-overload cardiac hypertrophy
Am J Physiol Heart Circ Physiol 290: H1635-H1641, 2006. First published November 4, 2005; doi:10.1152/ajpheart.00612.2005 [Abstract] [Full Text] [PDF]  

Jureta W. Horton, David L. Maass, and D. Jean White

Hypertonic saline dextran after burn injury decreases inflammatory cytokine responses to subsequent pneumonia-related sepsis
Am J Physiol Heart Circ Physiol 290: H1642-H1650, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00586.2005 [Abstract] [Full Text] [PDF]  

Ram Sharony, Giuseppe Pintucci, Paul C. Saunders, Eugene A. Grossi, F. Gregory Baumann, Aubrey C. Galloway, and Paolo Mignatti

Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2
Am J Physiol Heart Circ Physiol 290: H1651-H1659, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00530.2005 [Abstract] [Full Text] [PDF]  

Utako Yokoyama, Susumu Minamisawa, Satomi Adachi-Akahane, Toru Akaike, Isao Naguro, Kengo Funakoshi, Mari Iwamoto, Masamichi Nakagome, Nobuyuki Uemura, Hideaki Hori, Shumpei Yokota, and Yoshihiro Ishikawa

Multiple transcripts of Ca²⁺ channel ₁-subunits and a novel spliced variant of the _1C-subunit in rat ductus arteriosus
Am J Physiol Heart Circ Physiol 290: H1660-H1670, 2006. First published November 4, 2005; doi:10.1152/ajpheart.00100.2004 [Abstract] [Full Text] [PDF]  

Rolando E. Rumbaut, Ricardo V. Bellera, Jaspreet K. Randhawa, Corie N. Shrimpton, Swapan K. Dasgupta, Jing-Fei Dong, and Alan R. Burns

Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanism
Am J Physiol Heart Circ Physiol 290: H1671-H1679, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00305.2005 [Abstract] [Full Text] [PDF]  

Monica Kukielka, Douglas R. Seals, and George E. Billman

Cardiac vagal modulation of heart rate during prolonged submaximal exercise in animals with healed myocardial infarctions: effects of training
Am J Physiol Heart Circ Physiol 290: H1680-H1685, 2006. First published December 9, 2005; doi:10.1152/ajpheart.01034.2005 [Abstract] [Full Text] [PDF]  

Yong-Mei Cha, Petras P. Dzeja, Margaret M. Redfield, Win K. Shen, and Andre Terzic

Bioenergetic protection of failing atrial and ventricular myocardium by vasopeptidase inhibitor omapatrilat
Am J Physiol Heart Circ Physiol 290: H1686-H1692, 2006. First published December 9, 2005; doi:10.1152/ajpheart.00384.2005 [Abstract] [Full Text] [PDF]  

Alexandra Luksch, Barbara Wimpissinger, Kaija Polak, Kerstin Jandrasits, and Leopold Schmetterer

ET_a-receptor blockade, but not ACE inhibition, blunts retinal vessel response during isometric exercise
Am J Physiol Heart Circ Physiol 290: H1693-H1698, 2006. First published December 3, 2005; doi:10.1152/ajpheart.00947.2005 [Abstract] [Full Text] [PDF]  

K. A. Connelly, D. L. Prior, D. J. Kelly, M. P. Feneley, H. Krum, and R. E. Gilbert

Load-sensitive measures may overestimate global systolic function in the presence of left ventricular hypertrophy: a comparison with load-insensitive measures
Am J Physiol Heart Circ Physiol 290: H1699-H1705, 2006. First published November 4, 2005; doi:10.1152/ajpheart.00577.2005 [Abstract] [Full Text] [PDF]  

Henry Krum, Elisabeth Lambert, Emma Windebank, Duncan J. Campbell, and Murray Esler

Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension
Am J Physiol Heart Circ Physiol 290: H1706-H1712, 2006. First published November 11, 2005; doi:10.1152/ajpheart.00885.2005 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Bunyen Teng, Habib R. Ansari, Peter J. Oldenburg, J. Schnermann, and S. Jamal Mustafa

Isolation and characterization of coronary endothelial and smooth muscle cells from A₁ adenosine receptor-knockout mice
Am J Physiol Heart Circ Physiol 290: H1713-H1720, 2006. First published November 18, 2005; doi:10.1152/ajpheart.00826.2005 [Abstract] [Full Text] [PDF]  

CORRIGENDUM:

CORRIGENDUM
Am J Physiol Heart Circ Physiol 290: H1727-H1727, 2006; doi:10.1152/ajpheart.00012.2006 [Full Text] [PDF]  

REPORTS:

Chiara d'Agostino, Volodymyr Labinskyy, Vincenzo Lionetti, Margaret P. Chandler, Biao Lei, Ken Matsuo, Michelle Bellomo, Xiaobin Xu, Thomas H. Hintze, William C. Stanley, and Fabio A. Recchia

Altered cardiac metabolic phenotype after prolonged inhibition of NO synthesis in chronically instrumented dogs
Am J Physiol Heart Circ Physiol 290: H1721-H1726, 2006. First published January 20, 2006; doi:10.1152/ajpheart.00745.2005 [Abstract] [Full Text] [PDF]  

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