INVITED REVIEWS:

Matthias L. Riess, David F. Stowe, and David C. Warltier

Cardiac pharmacological preconditioning with volatile anesthetics: from bench to bedside?
Am J Physiol Heart Circ Physiol 286: H1603-H1607, 2004; 10.1152/ajpheart.00963.2003 [Abstract] [Full Text] [PDF]  

EDITORIAL:

James R. Sowers

Insulin resistance and hypertension
Am J Physiol Heart Circ Physiol 286: H1597-H1602, 2004; 10.1152/ajpheart.00026.2004 [Abstract] [Full Text] [PDF]  

ARTICLES:

Katherine C. Wood, Robert P. Hebbel, and D. Neil Granger

Endothelial cell P-selectin mediates a proinflammatory and prothrombogenic phenotype in cerebral venules of sickle cell transgenic mice
Am J Physiol Heart Circ Physiol 286: H1608-H1614, 2004. First published January 2, 2004; 10.1152/ajpheart.01056.2003 [Abstract] [Full Text] [PDF]  

DaLiao Xiao, William J. Pearce, Lawrence D. Longo, and Lubo Zhang

ERK-mediated uterine artery contraction: role of thick and thin filament regulatory pathways
Am J Physiol Heart Circ Physiol 286: H1615-H1622, 2004; 10.1152/ajpheart.00981.2003 [Abstract] [Full Text] [PDF]  

Tara L. Christie, Rickie Mui, Thomas W. White, and Gunnar Valdimarsson

Molecular cloning, functional analysis, and RNA expression analysis of connexin45.6: a zebrafish cardiovascular connexin
Am J Physiol Heart Circ Physiol 286: H1623-H1632, 2004. First published January 2, 2004; 10.1152/ajpheart.00800.2003 [Abstract] [Full Text] [PDF]  

Andrey V. Kuznetsov, Stefan Schneeberger, Rüdiger Seiler, Gerald Brandacher, Walter Mark, Wolfgang Steurer, Valdur Saks, Yves Usson, Raimund Margreiter, and Erich Gnaiger

Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion
Am J Physiol Heart Circ Physiol 286: H1633-H1641, 2004. First published December 23, 2003; 10.1152/ajpheart.00701.2003 [Abstract] [Full Text] [PDF]  

Virginia L. Brooks, Korrina L. Freeman, and Kathy A. Clow

Excitatory amino acids in rostral ventrolateral medulla support blood pressure during water deprivation in rats
Am J Physiol Heart Circ Physiol 286: H1642-H1648, 2004. First published January 8, 2004; 10.1152/ajpheart.01004.2003 [Abstract] [Full Text] [PDF]  

Yiru Guo, Adam B. Stein, Wen-Jian Wu, Wei Tan, Xiaoping Zhu, Qian-Hong Li, Buddhadeb Dawn, Roberto Motterlini, and Roberto Bolli

Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo
Am J Physiol Heart Circ Physiol 286: H1649-H1653, 2004. First published January 2, 2004; 10.1152/ajpheart.00971.2003 [Abstract] [Full Text] [PDF]  

Fang Hua, Brian A. Ricketts, Angela Reifsteck, Jeffrey L. Ardell, and Carole A. Williams

Myocardial ischemia induces the release of substance P from cardiac afferent neurons in rat thoracic spinal cord
Am J Physiol Heart Circ Physiol 286: H1654-H1664, 2004. First published December 18, 2003; 10.1152/ajpheart.00906.2003 [Abstract] [Full Text] [PDF]  

Junhui Tan, Hao Wang, and Frans H. H. Leenen

Increases in brain and cardiac AT₁ receptor and ACE densities after myocardial infarct in rats
Am J Physiol Heart Circ Physiol 286: H1665-H1671, 2004. First published December 23, 2003; 10.1152/ajpheart.00858.2003 [Abstract] [Full Text] [PDF]  

A. W. Mulivor and H. H. Lipowsky

Inflammation- and ischemia-induced shedding of venular glycocalyx
Am J Physiol Heart Circ Physiol 286: H1672-H1680, 2004. First published January 2, 2004; 10.1152/ajpheart.00832.2003 [Abstract] [Full Text] [PDF]  

Fruzsina K. Johnson, William Durante, Kelly J. Peyton, and Robert A. Johnson

Heme oxygenase-mediated endothelial dysfunction in DOCA-salt, but not in spontaneously hypertensive, rat arterioles
Am J Physiol Heart Circ Physiol 286: H1681-H1687, 2004. First published December 23, 2003; 10.1152/ajpheart.00409.2003 [Abstract] [Full Text] [PDF]  

Cuiling Liu, Simon Mather, Yu Huang, Christopher J. Garland, and Xiaoqiang Yao

Extracellular ATP facilitates flow-induced vasodilatation in rat small mesenteric arteries
Am J Physiol Heart Circ Physiol 286: H1688-H1695, 2004. First published January 8, 2004; 10.1152/ajpheart.00576.2003 [Abstract] [Full Text] [PDF]  

Motoyuki Iemitsu, Takashi Miyauchi, Seiji Maeda, Takumi Tanabe, Masakatsu Takanashi, Mitsuo Matsuda, and Iwao Yamaguchi

Exercise training improves cardiac function-related gene levels through thyroid hormone receptor signaling in aged rats
Am J Physiol Heart Circ Physiol 286: H1696-H1705, 2004. First published January 2, 2004; 10.1152/ajpheart.00761.2003 [Abstract] [Full Text] [PDF]  

Lie Gao, Zhen Zhu, Irving H. Zucker, and Wei Wang

Cardiac sympathetic afferent stimulation impairs baroreflex control of renal sympathetic nerve activity in rats
Am J Physiol Heart Circ Physiol 286: H1706-H1711, 2004; 10.1152/ajpheart.01097.2003 [Abstract] [Full Text] [PDF]  

Guohu Li, Soochan Bae, and Lubo Zhang

Effect of prenatal hypoxia on heat stress-mediated cardioprotection in adult rat heart
Am J Physiol Heart Circ Physiol 286: H1712-H1719, 2004. First published January 8, 2004; 10.1152/ajpheart.00898.2003 [Abstract] [Full Text] [PDF]  

Surovi Hazarika, Michael R. Van Scott, and Robert M. Lust

Myocardial ischemia-reperfusion injury is enhanced in a model of systemic allergy and asthma
Am J Physiol Heart Circ Physiol 286: H1720-H1725, 2004. First published January 8, 2004; 10.1152/ajpheart.01064.2003 [Abstract] [Full Text] [PDF]  

Xianming Lin and Richard D. Veenstra

Action potential modulation of connexin40 gap junctional conductance
Am J Physiol Heart Circ Physiol 286: H1726-H1735, 2004. First published December 23, 2003; 10.1152/ajpheart.00943.2003 [Abstract] [Full Text] [PDF]  

S. Volianitis, C. C. Yoshiga, P. Nissen, and N. H. Secher

Effect of fitness on arm vascular and metabolic responses to upper body exercise
Am J Physiol Heart Circ Physiol 286: H1736-H1741, 2004. First published December 18, 2003; 10.1152/ajpheart.01001.2003 [Abstract] [Full Text] [PDF]  

Kalyan C. Vinnakota and James B. Bassingthwaighte

Myocardial density and composition: a basis for calculating intracellular metabolite concentrations
Am J Physiol Heart Circ Physiol 286: H1742-H1749, 2004. First published December 23, 2003; 10.1152/ajpheart.00478.2003 [Abstract] [Full Text] [PDF]  

Maxwell I. Ginsburg and Ann L. Baldwin

Disodium cromoglycate stabilizes mast cell degranulation while reducing the number of hemoglobin-induced microvascular leaks in rat mesentery
Am J Physiol Heart Circ Physiol 286: H1750-H1756, 2004. First published January 2, 2004; 10.1152/ajpheart.00605.2003 [Abstract] [Full Text] [PDF]  

Robert B. Clark, Matteo E. Mangoni, Andreas Lueger, Brigitte Couette, Joel Nargeot, and Wayne R. Giles

A rapidly activating delayed rectifier K⁺ current regulates pacemaker activity in adult mouse sinoatrial node cells
Am J Physiol Heart Circ Physiol 286: H1757-H1766, 2004. First published December 23, 2003; 10.1152/ajpheart.00753.2003 [Abstract] [Full Text] [PDF]  

Adrian T. Gonon, Deniz Erbas, Anders Bröijersén, Guro Valen, and John Pernow

Nitric oxide mediates protective effect of endothelin receptor antagonism during myocardial ischemia and reperfusion
Am J Physiol Heart Circ Physiol 286: H1767-H1774, 2004. First published December 23, 2003; 10.1152/ajpheart.00544.2003 [Abstract] [Full Text] [PDF]  

John E. Jones, Jennifer L. Walker, Yanli Song, Norbert Weiss, Wellington V. Cardoso, Rubin M. Tuder, Joseph Loscalzo, and Ying-Yi Zhang

Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats
Am J Physiol Heart Circ Physiol 286: H1775-H1784, 2004. First published January 15, 2004; 10.1152/ajpheart.00281.2003 [Abstract] [Full Text] [PDF]  

David G. Soergel, Dimitrios Georgakopoulos, Linda B. Stull, David A. Kass, and Anne M. Murphy

Augmented systolic response to the calcium sensitizer EMD-57033 in a transgenic model with troponin I truncation
Am J Physiol Heart Circ Physiol 286: H1785-H1792, 2004. First published December 23, 2003; 10.1152/ajpheart.00170.2003 [Abstract] [Full Text] [PDF]  

Javier Palacios, Elisa T. Marusic, Nandy C. Lopez, Magdalena Gonzalez, and Luis Michea

Estradiol-induced expression of Na⁺-K⁺-ATPase catalytic isoforms in rat arteries: gender differences in activity mediated by nitric oxide donors
Am J Physiol Heart Circ Physiol 286: H1793-H1800, 2004. First published January 2, 2004; 10.1152/ajpheart.00990.2003 [Abstract] [Full Text] [PDF]  

Michael C. Payne, Hai-Ying Zhang, Yuichi Shirasawa, Yasuhiko Koga, Mitsuo Ikebe, Joseph N. Benoit, and Steven A. Fisher

Dynamic changes in expression of myosin phosphatase in a model of portal hypertension
Am J Physiol Heart Circ Physiol 286: H1801-H1810, 2004. First published January 2, 2004; 10.1152/ajpheart.00696.2003 [Abstract] [Full Text] [PDF]  

Luciana N. Torres, Ivo P. Torres Filho, R. Wayne Barbee, M. Hakam Tiba, Kevin R. Ward, and Roland N. Pittman

Systemic responses to prolonged hemorrhagic hypotension
Am J Physiol Heart Circ Physiol 286: H1811-H1820, 2004. First published January 15, 2004; 10.1152/ajpheart.00837.2003 [Abstract] [Full Text] [PDF]  

Arja L. T. Uusitalo, Tomi Laitinen, Sari B. Väisänen, Esko Länsimies, and Rainer Rauramaa

Physical training and heart rate and blood pressure variability: a 5-yr randomized trial
Am J Physiol Heart Circ Physiol 286: H1821-H1826, 2004. First published January 15, 2004; 10.1152/ajpheart.00600.2003 [Abstract] [Full Text] [PDF]  

Jonathan P. Alberding, Ann L. Baldwin, Jennifer K. Barton, and Elizabeth Wiley

Onset of pulsatile pressure causes transiently increased filtration through artery wall
Am J Physiol Heart Circ Physiol 286: H1827-H1835, 2004. First published January 15, 2004; 10.1152/ajpheart.01059.2003 [Abstract] [Full Text] [PDF]  

Chikaya Omichi, Scott T. Lamp, Shien-Fong Lin, Junzhong Yang, Ali Baher, Shengmei Zhou, Mina Attin, Moon-Hyoung Lee, Hrayr S. Karagueuzian, Boris Kogan, Zhilin Qu, Alan Garfinkel, Peng-Sheng Chen, and James N. Weiss

Intracellular Ca dynamics in ventricular fibrillation
Am J Physiol Heart Circ Physiol 286: H1836-H1844, 2004. First published January 2, 2004; 10.1152/ajpheart.00123.2003 [Abstract] [Full Text] [PDF]  

Jun-ichi Kawabe, Satoshi Okumura, Ming-Chih Lee, Junichi Sadoshima, and Yoshihiro Ishikawa

Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle cells
Am J Physiol Heart Circ Physiol 286: H1845-H1852, 2004; 10.1152/ajpheart.00593.2003 [Abstract] [Full Text] [PDF]  

Darlene K. Racker

The AV junction region of the heart: a comprehensive study correlating gross anatomy and direct three-dimensional analysis. Part II. Morphology and cytoarchitecture
Am J Physiol Heart Circ Physiol 286: H1853-H1871, 2004; 10.1152/ajpheart.01205.2003 [Abstract] [Full Text] [PDF]  

J. J. M. Zwanenburg, M. J. W. Götte, J. P. A. Kuijer, R. M. Heethaar, A. C. van Rossum, and J. T. Marcus

Timing of cardiac contraction in humans mapped by high-temporal-resolution MRI tagging: early onset and late peak of shortening in lateral wall
Am J Physiol Heart Circ Physiol 286: H1872-H1880, 2004. First published January 15, 2004; 10.1152/ajpheart.01047.2003 [Abstract] [Full Text] [PDF]  

Chung-Hyun Cho, Chang Sup Lee, Mikyung Chang, Il-Ho Jang, Soo Jin Kim, Inhwan Hwang, Sung Ho Ryu, Chin O. Lee, and Gou Young Koh

Localization of VEGFR-2 and PLD₂ in endothelial caveolae is involved in VEGF-induced phosphorylation of MEK and ERK
Am J Physiol Heart Circ Physiol 286: H1881-H1888, 2004. First published January 2, 2004; 10.1152/ajpheart.00786.2003 [Abstract] [Full Text] [PDF]  

Xiao Lu, Xiaomei Guo, Carlos Linares, and Ghassan S. Kassab

A new method to denude the endothelium without damage to media: structural, functional, and biomechanical validation
Am J Physiol Heart Circ Physiol 286: H1889-H1894, 2004; 10.1152/ajpheart.00863.2003 [Abstract] [Full Text] [PDF]  

Dianne Cooper, Janice Russell, Keith D. Chitman, Matthew C. Williams, Robert E. Wolf, and D. Neil Granger

Leukocyte dependence of platelet adhesion in postcapillary venules
Am J Physiol Heart Circ Physiol 286: H1895-H1900, 2004. First published January 8, 2004; 10.1152/ajpheart.01000.2003 [Abstract] [Full Text] [PDF]  

Imad Libbus, Xiaoping Wan, and David S. Rosenbaum

Electrotonic load triggers remodeling of repolarizing current I_to in ventricle
Am J Physiol Heart Circ Physiol 286: H1901-H1909, 2004. First published January 8, 2004; 10.1152/ajpheart.00581.2003 [Abstract] [Full Text] [PDF]  

Sergey V. Brodsky, Fan Zhang, Alberto Nasjletti, and Michael S. Goligorsky

Endothelium-derived microparticles impair endothelial function in vitro
Am J Physiol Heart Circ Physiol 286: H1910-H1915, 2004; 10.1152/ajpheart.01172.2003 [Abstract] [Full Text] [PDF]  

Heather A. Himburg, Deborah M. Grzybowski, Andrew L. Hazel, Jeffrey A. LaMack, Xue-Mei Li, and Morton H. Friedman

Spatial comparison between wall shear stress measures and porcine arterial endothelial permeability
Am J Physiol Heart Circ Physiol 286: H1916-H1922, 2004. First published January 8, 2004; 10.1152/ajpheart.00897.2003 [Abstract] [Full Text] [PDF]  

James D. McCully, Hidetaka Wakiyama, Yng-Ju Hsieh, Mara Jones, and Sidney Levitsky

Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol 286: H1923-H1935, 2004. First published January 8, 2004; 10.1152/ajpheart.00935.2003 [Abstract] [Full Text] [PDF]  

Chung-Chuan Chou, Shengmei Zhou, Yasushi Miyauchi, Hui-Nam Pak, Yuji Okuyama, Michael C. Fishbein, Hrayr S. Karagueuzian, and Peng-Sheng Chen

Effects of procainamide on electrical activity in thoracic veins and atria in canine model of sustained atrial fibrillation
Am J Physiol Heart Circ Physiol 286: H1936-H1945, 2004; 10.1152/ajpheart.00754.2003 [Abstract] [Full Text] [PDF]  

Alejandro N. Mazzadi, Marc F. Janier, Benjamin Brossier, Xavier André-Fouët, Eugene McFadden, Didier Revel, and Pierre Croisille

Dobutamine-tagged MRI for inotropic reserve assessment in severe CAD: relationship with PET findings
Am J Physiol Heart Circ Physiol 286: H1946-H1953, 2004. First published January 15, 2004; 10.1152/ajpheart.00704.2003 [Abstract] [Full Text] [PDF]  

Mohammed El Mabrouk, Quy N. Diep, Karim Benkirane, Rhian M. Touyz, and Ernesto L. Schiffrin

SAM68: a downstream target of angiotensin II signaling in vascular smooth muscle cells in genetic hypertension
Am J Physiol Heart Circ Physiol 286: H1954-H1962, 2004. First published December 23, 2003; 10.1152/ajpheart.00134.2003 [Abstract] [Full Text] [PDF]  

Srinivas M. Tipparaju, Rajiv Kumar, Yanggan Wang, Ronald W. Joyner, and Mary B. Wagner

Developmental differences in L-type calcium current of human atrial myocytes
Am J Physiol Heart Circ Physiol 286: H1963-H1969, 2004. First published January 8, 2004; 10.1152/ajpheart.01011.2003 [Abstract] [Full Text] [PDF]  

Robert A. Rose, Alan E. Lomax, Colleen S. Kondo, Madhu B. Anand-Srivastava, and Wayne R. Giles

Effects of C-type natriuretic peptide on ionic currents in mouse sinoatrial node: a role for the NPR-C receptor
Am J Physiol Heart Circ Physiol 286: H1970-H1977, 2004. First published January 2, 2004; 10.1152/ajpheart.00893.2003 [Abstract] [Full Text] [PDF]  

Astrid Parenti, Lydia Bellik, Laura Brogelli, Sandra Filippi, and Fabrizio Ledda

Endogenous VEGF-A is responsible for mitogenic effects of MCP-1 on vascular smooth muscle cells
Am J Physiol Heart Circ Physiol 286: H1978-H1984, 2004. First published December 23, 2003; 10.1152/ajpheart.00414.2003 [Abstract] [Full Text] [PDF]  

Chunlin Wang, Chunhua Jiao, Heather D. Hanlon, Wei Zheng, Robert J. Tomanek, and Gina C. Schatteman

Mechanical, cellular, and molecular factors interact to modulate circulating endothelial cell progenitors
Am J Physiol Heart Circ Physiol 286: H1985-H1993, 2004. First published January 8, 2004; 10.1152/ajpheart.00431.2003 [Abstract] [Full Text] [PDF]  

Wei Zheng, Robert M. Weiss, Xinguo Wang, Ruifeng Zhou, Angie M. Arlen, Li Lei, Eric Lazartigues, and Robert J. Tomanek

DITPA stimulates arteriolar growth and modifies myocardial postinfarction remodeling
Am J Physiol Heart Circ Physiol 286: H1994-H2000, 2004; 10.1152/ajpheart.00991.2003 [Abstract] [Full Text] [PDF]  

Steven Poelzing, Fadi G. Akar, Elvera Baron, and David S. Rosenbaum

Heterogeneous connexin43 expression produces electrophysiological heterogeneities across ventricular wall
Am J Physiol Heart Circ Physiol 286: H2001-H2009, 2004. First published January 2, 2004; 10.1152/ajpheart.00987.2003 [Abstract] [Full Text] [PDF]  

Jose A. Ospina, Holly N. Brevig, Diana N. Krause, and Sue P. Duckles

Estrogen suppresses IL-1-mediated induction of COX-2 pathway in rat cerebral blood vessels
Am J Physiol Heart Circ Physiol 286: H2010-H2019, 2004. First published December 18, 2003; 10.1152/ajpheart.00481.2003 [Abstract] [Full Text] [PDF]  

Hao-Liang Xu, Vitaliy Gavrilyuk, Hailemariam M. Wolde, Verna L. Baughman, and Dale A. Pelligrino

Regulation of rat pial arteriolar smooth muscle relaxation in vivo through multidrug resistance protein 5-mediated cGMP efflux
Am J Physiol Heart Circ Physiol 286: H2020-H2027, 2004. First published January 8, 2004; 10.1152/ajpheart.01105.2003 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Helge Wiig, Ellen Berggreen, Bengt Åge Sørby Borge, and Per Ole Iversen

Demonstration of altered signaling responses in bone marrow extracellular fluid during increased hematopoiesis in rats using a centrifugation method
Am J Physiol Heart Circ Physiol 286: H2028-H2034, 2004. First published January 8, 2004; 10.1152/ajpheart.00934.2003 [Abstract] [Full Text] [PDF]  

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