| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Heart and Circulatory Physiology, Vol 272, Issue 3 1157-H1164, Copyright © 1997 by American Physiological Society
ARTICLES |
F. Iellamo, J. M. Legramante, G. Raimondi and G. Peruzzi
Fisiopatologia Medica, Dipartimento di Medicina Interna, Universita di Roma Tor Vergata, Rome, Italy.
This study evaluated the influence of central command and muscle afferent stimulation (mechanical and chemical) on the integrated arterial baroreflex control of the sinus node during dynamic exercise. Twenty-two healthy men performed voluntary knee extension and electrically induced dynamic knee extension under free-flow and arrested-flow (n = 18) conditions. Systolic arterial pressure (SAP) and pulse interval (PI) were measured continuously and noninvasively. The arterial baroreflex was evaluated by analyzing the slopes of sequences of three or more consecutive beats characterized by the SAP and PI of the following beat; both increased or decreased in a linear fashion. Compared with rest, both voluntary exercise and electrically induced exercise under arrested-flow conditions resulted in a maintained baroreflex sensitivity (BRS; 11.7 +/- 1.2 vs. 9.6 +/- 0.7 and 11.3 +/- 1.4 vs. 9.8 +/- 1.5 ms/mmHg, respectively; not significant), with an apparent rightward shift in the regression line relating SAP to PI. Electrically induced exercise under free-flow conditions resulted in a significant decrease in BRS (12.1 +/- 1.4 vs. 8.8 +/- 0.8 ms/mmHg; P < 0.05). These data suggest that the central command and muscle chemoreflex act to preserve the BRS, possibly "resetting" the baroreceptor-cardiac response relationship, whereas stimulation of mechanosensitive receptors appears capable of modifying the integrated baroreflex control of sinus node function in humans. The first two mechanisms seem, however, to overwhelm the latter to maintain BRS, thus permitting a concomitant increase in arterial pressure and heart rate.
This article has been cited by other articles:
|
|
 |
|
  R. C. Drew, D. B. McIntyre, C. Ring, and M. J. White Local metabolite accumulation augments passive muscle stretch-induced modulation of carotid-cardiac but not carotid-vasomotor baroreflex sensitivity in man Exp Physiol, September 1, 2008; 93(9): 1044 - 1057. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Yamamoto, T. Kawada, A. Kamiya, H. Takaki, T. Shishido, K. Sunagawa, and M. Sugimachi Muscle mechanoreflex augments arterial baroreflex-mediated dynamic sympathetic response to carotid sinus pressure Am J Physiol Heart Circ Physiol, September 1, 2008; 295(3): H1081 - H1089. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Ichinose, M. Saito, N. Fujii, T. Ogawa, K. Hayashi, N. Kondo, and T. Nishiyasu Modulation of the control of muscle sympathetic nerve activity during incremental leg cycling J. Physiol., June 1, 2008; 586(11): 2753 - 2766. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Fisher, C. N. Young, and P. J. Fadel Effect of muscle metaboreflex activation on carotid-cardiac baroreflex function in humans Am J Physiol Heart Circ Physiol, May 1, 2008; 294(5): H2296 - H2304. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. P. Fisher, S. Ogoh, C. N. Young, D. M. Keller, and P. J. Fadel Exercise intensity influences cardiac baroreflex function at the onset of isometric exercise in humans J Appl Physiol, September 1, 2007; 103(3): 941 - 947. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Sala-Mercado, M. Ichinose, R. L. Hammond, T. Ichinose, M. Pallante, L. W. Stephenson, D. S. O'Leary, and F. Iellamo Muscle metaboreflex attenuates spontaneous heart rate baroreflex sensitivity during dynamic exercise Am J Physiol Heart Circ Physiol, June 1, 2007; 292(6): H2867 - H2873. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ogoh, J. P. Fisher, P. J. Fadel, and P. B. Raven Increases in central blood volume modulate carotid baroreflex resetting during dynamic exercise in humans J. Physiol., May 15, 2007; 581(1): 405 - 418. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Legramante, F. Iellamo, M. Massaro, S. Sacco, and A. Galante Effects of residential exercise training on heart rate recovery in coronary artery patients Am J Physiol Heart Circ Physiol, January 1, 2007; 292(1): H510 - H515. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Lador, M. Azabji Kenfack, C. Moia, M. Cautero, D. R. Morel, C. Capelli, and G. Ferretti Simultaneous determination of the kinetics of cardiac output, systemic O2 delivery, and lung O2 uptake at exercise onset in men Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2006; 290(4): R1071 - R1079. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ichinose, M. Saito, N. Kondo, and T. Nishiyasu Time-dependent modulation of arterial baroreflex control of muscle sympathetic nerve activity during isometric exercise in humans Am J Physiol Heart Circ Physiol, April 1, 2006; 290(4): H1419 - H1426. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. W. Sheel, F. Iellamo, P. B. Raven, and R. D. Wurster Commentary on Point-Counterpoint J Appl Physiol, January 1, 2006; 100(1): 371 - 371. [Full Text] [PDF]
|
|
|
|
|
|
A. M. Degtyarenko and M. P. Kaufman MLR-induced inhibition of barosensory cells in the NTS Am J Physiol Heart Circ Physiol, December 1, 2005; 289(6): H2575 - H2584. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yamamoto, T. Kawada, A. Kamiya, H. Takaki, M. Sugimachi, and K. Sunagawa Static interaction between muscle mechanoreflex and arterial baroreflex in determining efferent sympathetic nerve activity Am J Physiol Heart Circ Physiol, October 1, 2005; 289(4): H1604 - H1609. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Smith, J. H. Mitchell, and J. Li Independent modification of baroreceptor and exercise pressor reflex function by nitric oxide in nucleus tractus solitarius Am J Physiol Heart Circ Physiol, May 1, 2005; 288(5): H2068 - H2076. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Murata, K. Matsukawa, H. Komine, H. Tsuchimochi, and T. Nakamoto Central inhibition of the aortic baroreceptors-heart rate reflex at the onset of spontaneous muscle contraction J Appl Physiol, October 1, 2004; 97(4): 1371 - 1378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yamamoto, T. Kawada, A. Kamiya, H. Takaki, T. Miyamoto, M. Sugimachi, and K. Sunagawa Muscle mechanoreflex induces the pressor response by resetting the arterial baroreflex neural arc Am J Physiol Heart Circ Physiol, April 1, 2004; 286(4): H1382 - H1388. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Carrington, C. Ubolsakka, and M. J. White Interaction between muscle metaboreflex and mechanoreflex modulation of arterial baroreflex sensitivity in exercise J Appl Physiol, July 1, 2003; 95(1): 43 - 48. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Masuki, M. Takeoka, S.'I. Taniguchi, and H. Nose Enhanced baroreflex sensitivity in free-moving calponin knockout mice Am J Physiol Heart Circ Physiol, March 1, 2003; 284(3): H939 - H946. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Nishida, Q. H. Chen, M.-S. Zhou, and J. Horiuchi Sinoaortic denervation abolishes pressure resetting for daily physical activity in rabbits Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2002; 282(3): R649 - R657. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Cui, T. E. Wilson, M. Shibasaki, N. A. Hodges, and C. G. Crandall Baroreflex modulation of muscle sympathetic nerve activity during posthandgrip muscle ischemia in humans J Appl Physiol, October 1, 2001; 91(4): 1679 - 1686. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kamiya, D. Michikami, Q. Fu, Y. Niimi, S. Iwase, T. Mano, and A. Suzumura Static handgrip exercise modifies arterial baroreflex control of vascular sympathetic outflow in humans Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2001; 281(4): R1134 - R1139. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. McIlveen, S. G. Hayes, and M. P. Kaufman Both central command and exercise pressor reflex reset carotid sinus baroreflex Am J Physiol Heart Circ Physiol, April 1, 2001; 280(4): H1454 - H1463. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. G. Querry, S. A. Smith, M. Stromstad, K. Ide, P. B. Raven, and N. H. Secher Neural blockade during exercise augments central command's contribution to carotid baroreflex resetting Am J Physiol Heart Circ Physiol, April 1, 2001; 280(4): H1635 - H1644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Iellamo and J. R. G. M. D. H. Groeller Baroreflex control of heart rate during exercise: a topic of perennial conflict J Appl Physiol, March 1, 2001; 90(3): 1184 - 1185. [Full Text] [PDF]
|
|
|
|
|
|
P. J. Fadel, S. Ogoh, D. E. Watenpaugh, W. Wasmund, A. Olivencia-Yurvati, M. L. Smith, and P. B. Raven Carotid baroreflex regulation of sympathetic nerve activity during dynamic exercise in humans Am J Physiol Heart Circ Physiol, March 1, 2001; 280(3): H1383 - H1390. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Iellamo, J. M. Legramante, M. Massaro, G. Raimondi, and A. Galante Effects of a Residential Exercise Training on Baroreflex Sensitivity and Heart Rate Variability in Patients With Coronary Artery Disease : A Randomized, Controlled Study Circulation, November 21, 2000; 102(21): 2588 - 2592. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Van de Borne, S. Mezzetti, N. Montano, K. Narkiewicz, J. P. Degaute, and V. K. Somers Hyperventilation alters arterial baroreflex control of heart rate and muscle sympathetic nerve activity Am J Physiol Heart Circ Physiol, August 1, 2000; 279(2): H536 - H541. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Iellamo, P. Pizzinelli, M. Massaro, G. Raimondi, G. Peruzzi, and J. M. Legramante Muscle Metaboreflex Contribution to Sinus Node Regulation During Static Exercise : Insights From Spectral Analysis of Heart Rate Variability Circulation, July 6, 1999; 100(1): 27 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. H. Norton, R. Boushel, S. Strange, B. Saltin, and P. B. Raven Resetting of the carotid arterial baroreflex during dynamic exercise in humans J Appl Physiol, July 1, 1999; 87(1): 332 - 338. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. van de Borne, S. Heron, H. Nguyen, P. Unger, M. Leeman, J. L. Vincent, and J. P. Degaute Arterial Baroreflex Control of the Sinus Node During Dobutamine Exercise Stress Testing Hypertension, April 1, 1999; 33(4): 987 - 991. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Iellamo, M. Massaro, G. Raimondi, G. Peruzzi, and J. M. Legramante Role of muscular factors in cardiorespiratory responses to static exercise: contribution of reflex mechanisms J Appl Physiol, January 1, 1999; 86(1): 174 - 180. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. T. Potts and J. H. Mitchell Rapid resetting of carotid baroreceptor reflex by afferent input from skeletal muscle receptors Am J Physiol Heart Circ Physiol, December 1, 1998; 275(6): H2000 - H2008. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
