AJP - Heart AJP citation statistics
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 270: H1390-H1397, 1996;
0363-6135/96 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yaegashi, K.
Right arrow Articles by Morimoto, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yaegashi, K.
Right arrow Articles by Morimoto, T.

AJP - Heart and Circulatory Physiology, Vol 270, Issue 4 1390-H1397, Copyright © 1996 by American Physiological Society

ARTICLES

Diffusivity of oxygen in microvascular beds as determined from PO2 distribution maps

K. Yaegashi, T. Itoh, T. Kosaka, H. Fukushima and T. Morimoto
Department of Physiology, Kyoto Prefectural University of Medicine, Japan.

Dynamic changes in the distribution of PO2 in the rat mesentery were measured to determine the O2 diffusion coefficient (DO2) and consumption rate (VO2). The distribution of PO2 was obtained in two-dimensional maps by microscopic fluorometry on the basis of oxygen quenching. The corresponding vasculature was also recorded on a video recorder to analyze the PO2 distribution consistent with the arrangement of the microvessels. Anesthetized rats breathing room air were subjected to 100% O2 ventilation to induce dynamic changes in PO2 distribution. We assumed a homogenous and constant VO2 in the tissue, and a one-dimensional diffusion equation was applied to simulate oxygen transport. The PO2 data corresponded very well to the theoretical curves, and calculated DO2 was 1.04 +/- 0.78 X 10(-5) cm2/s (mean +/- SD, n = 38) and VO2 was 8.2 +/- 3.9 x 10(-6) cm3 O2.cm-3 tissue.s-1 (n = 27) at 37 degrees C. However, PO2 values at points remote from the arterioles remained higher than the theoretical prediction.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. S. Golub, M. C. Barker, and R. N. Pittman
Microvascular oxygen tension in the rat mesentery
Am J Physiol Heart Circ Physiol, January 1, 2008; 294(1): H21 - H28.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. S. Golub, M. C. Barker, and R. N. Pittman
PO2 profiles near arterioles and tissue oxygen consumption in rat mesentery
Am J Physiol Heart Circ Physiol, August 1, 2007; 293(2): H1097 - H1106.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
M. Paxian, S. A. Keller, B. Cross, T. T. Huynh, and M. G. Clemens
High-resolution visualization of oxygen distribution in the liver in vivo
Am J Physiol Gastrointest Liver Physiol, January 1, 2004; 286(1): G37 - G44.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
A. G. TSAI, P. C. JOHNSON, and M. INTAGLIETTA
Oxygen Gradients in the Microcirculation
Physiol Rev, July 1, 2003; 83(3): 933 - 963.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Shibata, S. Ichioka, J. Ando, and A. Kamiya
Microvascular and interstitial PO2 measurements in rat skeletal muscle by phosphorescence quenching
J Appl Physiol, July 1, 2001; 91(1): 321 - 327.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. G. Tsai, B. Friesenecker, M. C. Mazzoni, H. Kerger, D. G. Buerk, P. C. Johnson, and M. Intaglietta
Microvascular and tissue oxygen gradients in the rat mesentery
PNAS, June 9, 1998; 95(12): 6590 - 6595.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online