AJP - Heart Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 258: H1164-H1170, 1990;
0363-6135/90 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Barman, S. A.
Right arrow Articles by Taylor, A. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Barman, S. A.
Right arrow Articles by Taylor, A. E.

AJP - Heart and Circulatory Physiology, Vol 258, Issue 4 1164-H1170, Copyright © 1990 by American Physiological Society

ARTICLES

Effect of pulmonary venous pressure elevation on vascular resistance and compliance

S. A. Barman and A. E. Taylor
Department of Physiology, College of Medicine, University of South Alabama, Mobile 36688.

The effect of pulmonary venous pressure elevation on the longitudinal distribution of resistance and compliance in the canine pulmonary circulation was determined at control vascular tone and after vascular tone was increased with histamine. The arterial, venous, and double-occlusion techniques were used in isolated dog lungs blood perfused at constant flow. The large and small blood vessel resistances and compliances were studied under both vascular tone conditions when pulmonary venous pressure was elevated above isogravimetric venous pressure conditions in successive 5 cmH2O increments up to 30 cmH2O. The results of this study indicate that pulmonary venous pressure elevations to 20 cmH2O above isogravimetric venous pressure significantly decrease total vascular resistance by reducing both the small and large vein resistances, an effect which is more pronounced in the histamine-treated lungs. Also, under control vascular tone, both the middle compartment compliance and total compliance were greatly decreased over this pressure range. Histamine treatment significantly reduced both the large vessel and middle compartment compliances before and during low venous pressure elevation. When venous pressure was then raised to at least 25 cmH2O above control outflow pressure with histamine present, the middle compartment compliance was again significantly decreased.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
G. P. Topulos, R. E. Brown, and J. P. Butler
Influence of lung volume on pulmonary microvascular pressure-volume characteristics
J Appl Physiol, October 1, 2000; 89(4): 1591 - 1600.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. I. Townsley, K. S. Snell, C. L. Ivey, D. E. Culberson, D. C. Liu, R. K. Reed, and O. Mathieu-Costello
Remodeling of lung interstitium but not resistance vessels in canine pacing-induced heart failure
J Appl Physiol, November 1, 1999; 87(5): 1823 - 1830.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
L. E. Fisher Jr., A. Cziraki, C. M. Steinhart, and J. D. Catravas
Unaltered pulmonary capillary surface area in the presence of changing arterial resistance
Am J Physiol Lung Cell Mol Physiol, February 1, 1998; 274(2): L264 - L269.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
A. Theodorou, N. Weger, K. Kunke, K. Rhee, D. Bice, B. Muggenberg, and R. Lemen
Ragweed sensitization alters pulmonary vascular responses to bronchoprovocation in beagle dogs
J Appl Physiol, September 1, 1997; 83(3): 912 - 917.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online