AJP - Heart Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 251: H890-H896, 1986;
0363-6135/86 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lattion, A. L.
Right arrow Articles by Soubrier, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lattion, A. L.
Right arrow Articles by Soubrier, F.

AJP - Heart and Circulatory Physiology, Vol 251, Issue 5 890-H896, Copyright © 1986 by American Physiological Society

ARTICLES

Myocardial recruitment during ANF mRNA increase with volume overload in the rat

A. L. Lattion, J. B. Michel, E. Arnauld, P. Corvol and F. Soubrier

A synthetic oligonucleotide probe complementary to messenger ribonucleic acid (mRNA) encoding for the C-terminal portion of atrial natriuretic factor (ANF) has been used to study the expression of the ANF gene in rat myocardium. Four experimental models were studied: binephrectomy (for 48 h); ligature of both ureters (for 48 h); deoxycorticosterone acetate-salt (for 3 wk); and aortocaval fistula (for 2 wk). Analysis of atrial RNA by gel-blot hybridization detected a single band, corresponding in length to that of mRNA coding for ANF. Such an mRNA was also detected in ventricular RNA but was 1/50th as abundant. In the four experimental groups ANF mRNA was increased significantly as compared with controls. In all rats there was no significant difference in the ANF mRNA content between the left and the right atrium. Each experimental condition was accompanied by a highly significant increase in ANF gene expression in the left ventricle, where all of the ventricular tissue could be recruited and with a negative gradient from the base to the apex of the left ventricle. These data were confirmed by in situ hybridization. Thus all of the atrial and ventricular myocardium can express the ANF gene. Recruitment increases in response to passive stretch of the cardiac chambers.


This article has been cited by other articles:


Home page
 Exp. Biol. Med.Home page
S. H. Kim, G. Y. Koh, K. W. Cho, W.-Y. Park, and J.-S. Seo
Stretch-Activated Atrial Natriuretic Peptide Secretion in Atria with Heat Shock Protein 70 Overexpression
Experimental Biology and Medicine, February 1, 2003; 228(2): 200 - 206.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
S. Gupta, N. H. Purcell, A. Lin, and S. Sen
Activation of nuclear factor-{kappa}B is necessary for myotrophin-induced cardiac hypertrophy
J. Cell Biol., December 10, 2002; (2002) 200207149.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S. H. Kim, J. H. Han, C. Cao, S. Z. Kim, and K. W. Cho
Postnatal changes in inhibitory effect of C-type natriuretic peptide on secretion of ANP
Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2002; 282(6): R1672 - R1679.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
H. Yamakawa, T. Imamura, T. Matsuo, H. Onitsuka, Y. Tsumori, J. Kato, K. Kitamura, Y. Koiwaya, and T. Eto
Diastolic wall stress and ANG II in cardiac hypertrophy and gene expression induced by volume overload
Am J Physiol Heart Circ Physiol, December 1, 2000; 279(6): H2939 - H2946.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
T. Langenickel, I. Pagel, K. Hohnel, R. Dietz, and R. Willenbrock
Differential regulation of cardiac ANP and BNP mRNA in different stages of experimental heart failure
Am J Physiol Heart Circ Physiol, May 1, 2000; 278(5): H1500 - H1506.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. Ueno, T. Miyauchi, S. Sakai, T. Kobayashi, K. Goto, and I. Yamaguchi
Effects of physiological or pathological pressure load in vivo on myocardial expression of ET-1 and receptors
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 1999; 277(5): R1321 - R1330.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
S. Masciotra, S. Picard, and C. F. Deschepper
Cosegregation Analysis in Genetic Crosses Suggests a Protective Role for Atrial Natriuretic Factor Against Ventricular Hypertrophy
Circ. Res., June 25, 1999; 84(12): 1453 - 1458.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
M. Marttila, O. Vuolteenaho, D. Ganten, K. Nakao, and H. Ruskoaho
Synthesis and Secretion of Natriuretic Peptides in the Hypertensive TGR(mREN-2)27 Transgenic Rat
Hypertension, December 1, 1996; 28(6): 995 - 1004.
[Abstract] [Full Text]

Home page
 HypertensionHome page
R. Willenbrock, M. Scheuermann, K. Hohnel, F. C. Luft, and R. Dietz
Acute and Chronic Neutral Endopeptidase Inhibition in Rats With Aortocaval Shunt
Hypertension, June 1, 1996; 27(6): 1259 - 1266.
[Abstract] [Full Text]

Home page
 CirculationHome page
A. Calderone, N. Takahashi, N. J. Izzo Jr, C. M. Thaik, and W. S. Colucci
Pressure- and Volume-Induced Left Ventricular Hypertrophies Are Associated With Distinct Myocyte Phenotypes and Differential Induction of Peptide Growth Factor mRNAs
Circulation, November 1, 1995; 92(9): 2385 - 2390.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online